methyl (2E)-2-(5-hydroxy-3-oxo-4-phenylfuran-2-ylidene)-2-phenylacetate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 英文名称: methyl (2E)-2-(5-hydroxy-3-oxo-4-phenylfuran-2-ylidene)-2-phenylacetate
• 化学式: C₁₉H₁₄O₅
• 分子量: 322.3
• InChiKey: NLQPTDHMZUGQCX-BMRADRMJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] DIBENZOFURAN DERIVATIVES WITH ANTIBACTERIAL AND WOUND-HEALING ACTIVITY<br/>[FR] DÉRIVÉS DE DIBENZOFURANNE À ACTIVITÉ ANTIBACTÉRIENNE ET DE CICATRISATION DE PLAIES
  申请人：UNIV DEGLI STUDI MILANO

  公开号：WO2013189950A1

  公开（公告）日：2013-12-27

  Disclosed are dibenzofuran derivatives of usnic acid, compositions thereof and use thereof in dermatological or cosmetic formularions with antimicrobial, regenerative and anti-aging purposes.

  揭示了乌司酸的二苯并呋喃衍生物，以及它们的组合物，并将其用于具有抗菌、再生和抗衰老作用的皮肤科或化妆品配方中。
• METHODS OF DESIGNING, PREPARING, AND USING NOVEL PROTONOPHORES
  申请人：Martineau Louis C.

  公开号：US20140135359A1

  公开（公告）日：2014-05-15

  The present invention provides a computer-assisted method of generating a protonophore requiring the use of a computer including a processor. The method includes: designing the protonophore, calculating, using the processor, an estimated protonophoric activity; producing the protonophore if the estimated protonophoric activity corresponds to an U 50 of about 20 μM or less; and determining the uncoupling activity of the protonophore. The present invention also provides novel protonophores that meet the above requirement and their methods of use.

  本发明提供了一种利用计算机辅助的方法来生成需要使用处理器的质子载体。该方法包括：设计质子载体，使用处理器计算估计的质子载体活性；如果估计的质子载体活性对应于大约20微米或更少的U50，则生产质子载体；并确定质子载体的解耦活性。本发明还提供了符合上述要求的新型质子载体及其使用方法。
• Rust disease control by Aphanocladium album and/or Beauveria brongniartii
  申请人：Subbiah Ven

  公开号：US20070110726A1

  公开（公告）日：2007-05-17

  There is disclosed a method and composition for controlling rust disease in plants. Metabolites produced by Aphanocladium album mycoparasites are recovered and applied in an effective amount to plants at risk for acquiring rust disease More specifically, the application of the metabolite converts infective urediniospores that cause rust disease into non-infective teliospores. In a more specific aspect, the metabolite is reacted with another substance or under a specific reaction to result in a different compound which is also effective against rust disease.

  本发明揭示了一种用于控制植物锈病的方法和组合物。通过Aphanocladium album真菌寄生体产生的代谢物被提取并以有效量施用于有患锈病风险的植物上。更具体地，代谢物的施用将导致引起锈病的传染性锈子孢子转变为非传染性的子囊孢子。在更具体的方面，这种代谢物与另一种物质或在特定反应条件下反应，形成对锈病也有效的不同化合物。
• CARBOXYL-FUNCTIONALIZED SILICON-CONTAINING PRECURSOR COMPOUND OF VARIOUS ORGANIC CARBOXYLIC ACIDS
  申请人：Weissenbach Kerstin

  公开号：US20130037744A1

  公开（公告）日：2013-02-14

  The invention relates to a composition of a carboxyl-functionalized silicon-containing precursor compound of at least two different organic acids, said composition having two, three, or four carboxyl groups functionalized with various hydrocarbon groups according to formula I and/or II. Said carboxyl groups can be released as carboxylic acids and can be used as silane hydrolysis catalysts and/or silane condensation catalysts. The invention further relates to methods for producing the composition, to the use of the composition for cross-linking polymers, and to a formulation of the composition in the form of a masterbatch.

  本发明涉及至少两种不同有机酸的含有羧基的硅前体化合物的组合物，该组合物具有根据公式I和/或II用各种碳氢基团官能化的两个、三个或四个羧基。所述羧基可以释放为羧酸，并可用作硅烷水解催化剂和/或硅烷缩聚催化剂。本发明还涉及制备该组合物的方法，将该组合物用于交联聚合物的使用以及将该组合物制成母粒形式的配方。
• SILANOL CONDENSATION CATALYSTS FOR THE CROSS-LINKING OF FILLED AND UNFILLED POLYMER COMPOUNDS
  申请人：Weissenbach Kerstin

  公开号：US20110144278A1

  公开（公告）日：2011-06-16

  The invention relates to a composition of an organofunctional silane compound, particularly of a mono-unsaturated silane compound, and of an organic acid or a precursor compound which releases said organic acid, and to a method for the production of polymer compounds such as granulates and/or finished products from thermoplastic base polymers and/or monomers and/or prepolymers of the thermoplastic base polymer utilizing the composition, the organic acid, or the precursor compound which releases said organic acid. The invention also relates to the produced polymers, filled plastics such as, for example, granulates, finished products, molded bodies and/or articles such as pipes or cables. In addition, the invention relates to a kit containing the composition.

  本发明涉及一种有机官能硅烷化合物组成物，特别是一种单不饱和硅烷化合物和有机酸或释放所述有机酸的前体化合物，以及利用该组成物、有机酸或释放所述有机酸的前体化合物从热塑性基础聚合物和/或单体和/或预聚物制备高分子化合物，例如颗粒和/或成品产品的方法。本发明还涉及制备的聚合物、填充塑料，例如颗粒、成品、成型体和/或管道或电缆等物品。此外，本发明还涉及一种包含该组成物的工具包。