7-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: 7-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-ol
• 化学式: C₉H₁₁NO₂
• 分子量: 165.19
• InChiKey: WQCAQYPEYUZWIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  41.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors
  申请人：Incyte Corporation

  公开号：US10556908B2

  公开（公告）日：2020-02-11

  The present invention is directed to imidazo[1,2-a]pyrazine derivatives of Formula I, or a pharmaceutically acceptable salt thereof, which are LSD1 inhibitors useful in the treatment of diseases such as cancer.

  本发明涉及式 I 的咪唑并[1,2-a]吡嗪衍生物或其药学上可接受的盐，它们是治疗癌症等疾病的 LSD1 抑制剂。
• IMIDAZOPYRAZINES AS LSD1 INHIBITORS
  申请人：Incyte Corporation

  公开号：US20190106426A1

  公开（公告）日：2019-04-11

  The present invention is directed to imidazo[1,2-a]pyrazine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.