N-ethyl-N,3-dimethylcyclobutan-1-amine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-ethyl-N,3-dimethylcyclobutan-1-amine
• 化学式: C₈H₁₇N
• 分子量: 127.23
• InChiKey: HFSQSPOFICQGML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• METHODS OF TREATING NEURODEGENERATIVE CONDITIONS
  申请人：Oxeia Biopharmaceuticals, Inc.

  公开号：US20170121385A1

  公开（公告）日：2017-05-04

  The present disclosure provides methods for treating a neurodegenerative condition or situation in a subject in need thereof, comprising administering to the subject an effective amount of a compound comprising ghrelin or a ghrelin variant.
• METHODS OF TREATING TRAUMATIC BRAIN INJURY
  申请人：OXEIA BIOPHARMACEUTICALS, INC.

  公开号：US20170266257A1

  公开（公告）日：2017-09-21

  The present disclosure provides methods for treating traumatic brain injury and other neurological disorders in a subject in need thereof, comprising administering to the subject an effective amount of a composition comprising ghrelin or a ghrelin variant. This invention provides for methods for treating a severe or moderate traumatic brain injury in a patient wherein said method comprises administering to the subject suffering from said severe or moderate traumatic brain injury a therapeutic effective amount of ghrelin or a ghrelin variant or a composition comprising ghrelin or a ghrelin variant so as to treat said severe or moderate traumatic brain injury.
• METHODS OF TREATING MILD BRAIN INJURY
  申请人：OXEIA BIOPHARMACEUTICALS, INC.

  公开号：US20170281732A1

  公开（公告）日：2017-10-05

  The present disclosure provides methods for treating mild brain injury and other neurological disorders in a subject in need thereof, comprising administering to the subject an effective amount of a compound comprising a ghrelin or ghrelin variant. This invention provides for methods for treating a mild brain injury or concussion in a patient wherein said method comprises administering to the subject in need thereof suffering from said mild brain injury or concussion an effective amount of a ghrelin variant or a composition comprising a ghrelin variant so as to treat said mild brain injury or concussion.