2-methyl-6-octylphenol | 17901-33-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-methyl-6-octylphenol
• 英文别名: 2-octyl-6-methylphenol；octylcresol
• CAS: 17901-33-6
• 化学式: C₁₅H₂₄O
• 分子量: 220.355
• InChiKey: ULLJOEOHPLSIJP-UHFFFAOYSA-N

物化性质

• 沸点：
  165-166 °C(Press: 30 Torr)
• 密度：
  0.933±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  辛酸 在 盐酸 、 三氯化铝 、 amalgamated zinc 、 三氯氧磷 作用下， 生成 2-methyl-6-octylphenol
  参考文献：
  名称：

  Kawai et al., Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1956, vol. 76, p. 660,664

  摘要：

  DOI：

文献信息

• Insecticidal compounds
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0302626A2

  公开（公告）日：1989-02-08

  The invention provides novel, insecticidally active compounds of formula (I) : wherein X represents a group of formula : where either (i) R¹ and R² represent hydrogen, methyl, halo or haloalkyl, or (ii) R¹ represents hydrogen and R² represents either a group of formula R³(R⁴)C=CH- or a group of formula R³(R⁴)(R⁵)C-CH(R⁵)-, wherein R³ and R⁴ represent hydrogen, methyl, halo or haloalkyl and R⁵ represent chloro or bromo; and Y represents -C≡CR¹⁰ or -NH-N=C(R¹¹)R¹² where R¹⁰, R¹¹ and R¹² are selected from hydrogen, alkyl and haloalkyl, or Y represents -CH₂Z where Z is selected from halo, CN, N₃, CH₂CN, -OCOR⁶, -SCOR⁷, -OCO₂R⁷, -OR⁸, -SR⁸, -N(R¹⁵)R⁸, -OSO₂R⁹ and -ON=C(R¹³)R¹⁴, where R⁶ represents H, alkyl or haloalkyl, R⁷ and R⁹ represent alkyl or haloalkyl, R⁸ represents propargyl optionally substituted with one or more methyl groups, and R¹³, R¹⁴ and R¹⁵ represent alkyl. The invention also provides insecticidal compositions comprising the compounds of formula (I) and methods of controlling insect pests therewith, and processes and intermediates for their preparation.

  该发明提供了具有杀虫活性的新型化合物，其化学式为（I）：其中X代表化学式中的一个基团：其中（i）R¹和R²代表氢、甲基、卤素或卤代烷基，或（ii）R¹代表氢，R²代表化学式R³（R⁴）C=CH-或化学式R³（R⁴）（R⁵）C-CH（R⁵）-的基团，其中R³和R⁴代表氢、甲基、卤素或卤代烷基，R⁵代表氯或溴；Y代表-C≡CR¹⁰或-NH-N=C（R¹¹）R¹²，其中R¹⁰、R¹¹和R¹²选自氢、烷基和卤代烷基，或Y代表-CH₂Z，其中Z选自卤素、CN、N₃、CH₂CN、-OCOR⁶、-SCOR⁷、-OCO₂R⁷、-OR⁸、-SR⁸、-N（R¹⁵）R⁸、-OSO₂R⁹和-ON=C（R¹³）R¹⁴，其中R⁶代表H、烷基或卤代烷基，R⁷和R⁹代表烷基或卤代烷基，R⁸代表丙炔基，可选择性地取代一个或多个甲基基团，R¹³、R¹⁴和R¹⁵代表烷基。该发明还提供了包含化合物（I）的杀虫组合物，以及用于控制昆虫害虫的方法，以及用于其制备的过程和中间体。
• Aryl pyridones as insecticidal agents
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0367410A1

  公开（公告）日：1990-05-09

  Insecticidal compounds have the formula (I) wherein R¹, R², R⁴ and R⁵ are independently selected from hydrogen, halogen, nitro, lower alkyl optionally substituted by halogen, lower alkoxy optionally substituted by halogen and lower alkenyl optionally substituted by halogen; R³ is halogen, amino, mono- or di-(lower alkyl)-amino, lower alkyl substituted by halogen, lower alkoxy or lower alkenyl optionally substituted by halogen, provided that R³ is not monochloro or monobromo- methyl; R⁶ is oxygen or sulphur; R⁷ is hydrogen, halogen, lower alkyl or lower alkoxy or lower thioalkoxy optionally substituted by halogen; R⁸ is hydrogen, halogen, optionally substituted lower alkyl lower alkoxy or thioalkoxy, cyano, nitro, optionally substituted oximino, lower alkenyl, aryloxy, or amino or S(O)nR¹¹ wherein n is 0, 1 or 2 and R¹¹ is optionally substituted lower alkyl; R⁹ is hydrogen, or lower alkyl or alkenyl optionally substituted by halogen, or CO₂R¹² wherein R¹² is lower alkyl optionally substituted by halogen; and is nitro or cyano.

  杀虫化合物的化学式为（I），其中R¹、R²、R⁴和R⁵独立地选择自氢、卤素、硝基、可选用卤素取代的低烷基、可选用卤素取代的低烷氧基和可选用卤素取代的低烯基；R³为卤素、氨基、单或双-(低烷基)-氨基、可选用卤素取代的低烷基、低烷氧基或可选用卤素取代的低烯基，但R³不是单氯或单溴甲基；R⁶为氧或硫；R⁷为氢、卤素、低烷基、低烷氧基或可选用卤素取代的低硫代烷氧基；R⁸为氢、卤素、可选用低烷基、低烷氧基或硫代烷氧基取代的低烷基、氰基、硝基、可选用氧肟基取代的、可选用卤素取代的低烯基、芳氧基、氨基或S（O）nR¹¹，其中n为0、1或2，R¹¹为可选用卤素取代的低烷基；R⁹为氢、或可选用卤素取代的低烷基或烯基，或CO₂R¹²，其中R¹²为可选用卤素取代的低烷基；并且为硝基或氰基。
• Heterocyclic compounds
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0481604A1

  公开（公告）日：1992-04-22

  Compound of formula (I) have insecticidal activity wherein R¹ is cyano or is an optionally substituted amide or thioamide group; R², R³, R⁴, R⁵, R⁶ and R⁷ are defined substituents on the phenyl and heterocycic ring respectively; R⁹ is O or S; and R⁸ is an optionally substituted alkene, alkyne, cyclopropyl, epoxy or carboxy alkyl group.

  式(I)的化合物具有杀虫活性，其中R¹是氰基或者是一个可选的取代酰胺或硫酰胺基团；R²、R³、R⁴、R⁵、R⁶和R⁷是苯环和杂环环上的定义取代基；R⁹是O或S；R⁸是一个可选的取代烯烃、炔烃、环丙烷、环氧或羧基烷基团。
• [EN] BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES<br/>[FR] DERIVES DE BENZOXAZOLE ET DE BENZOTHIAZOLE
  申请人：ZENECA LIMITED

  公开号：WO1994006783A1

  公开（公告）日：1994-03-31

  (EN) The invention provides novel compounds of formula (I) having nematicidal, insecticidal, acaricidal and fungicidal properties, compositions comprising them and processes and intermediates for their preparation, wherein: X is oxygen or sulphur; n is 0, 1, or 2; R1, R2, R3, and R4 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted aryloxy, optionally substituted arylalkoxy, alkoxy, alkenyloxy, alkynyloxy, hydroxyalkyl, alkoxyalkyl, alkylthio, alkenylthio, alkynylthio, haloalkyl, haloalkenyl, haloalkynyl, haloalkoxy, haloalkenyloxy, haloalkynyloxy, haloalkylthio, haloalkenylthio, haloalkynylthio, halogen, hydroxy, cyano, nitro, -NR5R6, -NR7COR8, -NR9SO2R10, -N(SO2-R11)(SO2-R12), -COR13, -CONR14R15, -COOR16, -OCOR17, -OSO2R18, -SO2NR19R20, -SO2R21, -SOR22, -CSNR23R24, -SiR25R26R27, -OCH2CO2R28, -OCH2CH2CO2R29, -CONR30SO2R31 and -SO2Z; or an adjacent pair of R1, R2, R3 and R4 when taken together form a fused 5- or 6-membered carbocyclic or heterocyclic ring; R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, R25, R26, R27, R28, R29, R30 and R31 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, optionally substituted aryl and optionally substituted arylalkyl; and Z is halogen.(FR) L'invention concerne des nouveaux composés de formule (I) ayant des propriétés nématicides, insecticides, acaricides et fongicides, des compositions comprenant ces composés et des procédés ainsi que des intermédiaires pour leur préparation, formule dans laquelle X représente oxygène or soufre; n est égal à 0, 1, ou 2; R1, R2, R3 et R4 sont sélectionnés indépendamment parmi hydrogène, alkyle, alcényle, alcynyle, cycloalkyle, alkylcycloalkyle, aryle éventuellement substitué, arylalkyle éventuellement substitué, aryloxyl éventuellement substitué, arylalcoxy éventuellement substitué, alcoxy, alcényloxy, alcynyloxy, hydroxyalkyle, alcoxyalkyle, alkylthio, alcénylthio, alcynylthio, haloalkyle, haloalcényle, haloalcynyle, haloalcoxy, haloalcényloxy, haloalcynyloxy, haloalkylthio, haloalcénylthio, haloalcynylthio, halogène, hydroxy, cyano, nitro, -NR5R6, -NR7COR8, -NR9SO2R10, -N(SO2-R11)(SO2-R12), -COR13, -CONR14R15, -COOR16, -OCOR17, -OSO2R18, -SO2NR19R20, -SO2R21, -SOR22, -CSNR23R24, -SiR25R26R27, -OCH2CO2R28, -OCH2CH2CO2R29, -CONR30SO2R31 et -SO2Z; ou une paire adjacente de R1, R2, R3 et R4 lorsqu'ils sont pris ensemble forment un cycle carbocyclique ou hétérocyclique fusionné à 5 ou 6 chaînons; R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, R25, R26, R27, R28, R29, R30 et R31 sont sélectionnés indépendamment parmi hydrogène, alkyle, alcényle, alcynyle, haloalkyle, haloalcényle, haloalcynyle, aryle éventuellement substistué et arylalkyle éventuellement substitué; et Z représente halogène.

  本发明提供了具有线虫杀虫、杀虫、杀螨和杀菌性质的新型化合物，以及包含它们的组合物和制备它们的过程和中间体，其中：X代表氧或硫；n为0、1或2；R1、R2、R3和R4独立选择自氢、烷基、烯基、炔基、环烷基、烷基环烷基、可选择取代的芳基、可选择取代的芳基烷基、可选择取代的芳基氧基、可选择取代的芳基烷氧基、烷氧基、烯氧基、炔氧基、羟基烷基、烷氧基烷基、烷硫基、烯硫基、炔硫基、卤代烷基、卤代烯基、卤代炔基、卤代烷氧基、卤代烯氧基、卤代炔氧基、卤代烷硫基、卤代烯硫基、卤代炔硫基、卤素、羟基、氰基、硝基、-NR5R6、-NR7COR8、-NR9SO2R10、-N（SO2-R11）（SO2-R12）、-COR13、-CONR14R15、-COOR16、-OCOR17、-OSO2R18、-SO2NR19R20、-SO2R21、-SOR22、-CSNR23R24、-SiR25R26R27、-OCH2CO2R28、-OCH2CH2CO2R29、-CONR30SO2R31和-SO2Z；或当R1、R2、R3和R4中的相邻对在一起时形成融合的5-或6成员环烷环或杂环时；R5、R6、R7、R8、R9、R10、R11、R12、R13、R14、R15、R16、R17、R18、R19、R20、R21、R22、R23、R24、R25、R26、R27、R28、R29、R30和R31独立选择自氢、烷基、烯基、炔基、卤代烷基、卤代烯基、卤代炔基、可选择取代的芳基和可选择取代的芳基烷基；Z代表卤素。
• Materials and methods for killing nematodes and nematode eggs
  申请人：——

  公开号：US20020016330A1

  公开（公告）日：2002-02-07

  Methods and compositions for the control of nematodes are disclosed. Specifically, the subject anthelmintic compounds have been found to advantageously control nematodes at concentrations which are non-phytotoxic. The anthelmintic compounds can be used in conjunction with other nematicidal agents such as free fatty acids, fatty acid salts, avermectins, ivermectin, and milbemycin.

  本发明揭示了控制线虫的方法和组合物。具体而言，已发现该类驱虫剂化合物可以在非植物毒性浓度下有效地控制线虫。该类驱虫剂化合物可以与其他线虫杀虫剂（如游离脂肪酸、脂肪酸盐、阿维菌素、伊维菌素和米尔贝霉素）一起使用。