tetrakis(5-tert-butyl-2-hydroxy-3-trimethylsilylphenyl)ethene | 1050682-72-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: tetrakis(5-tert-butyl-2-hydroxy-3-trimethylsilylphenyl)ethene
• 英文别名: tetrakis(5-tert-butyl-2-hydroxy-3-trimethylsilylphenyl)ethylene；4-Tert-butyl-2-trimethylsilyl-6-[1,2,2-tris(5-tert-butyl-2-hydroxy-3-trimethylsilylphenyl)ethenyl]phenol；4-tert-butyl-2-trimethylsilyl-6-[1,2,2-tris(5-tert-butyl-2-hydroxy-3-trimethylsilylphenyl)ethenyl]phenol
• CAS: 1050682-72-8
• 化学式: C₅₄H₈₄O₄Si₄
• 分子量: 909.601
• InChiKey: XYVBSWCQAYBTNF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.89
• 重原子数：
  62
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  在 正丁基锂 、 水 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 0.17h， 以0.794 g的产率得到tetrakis(5-tert-butyl-2-hydroxy-3-trimethylsilylphenyl)ethene
  参考文献：
  名称：

  Ortho-Silylated Derivatives of Tetrakis(2-hydroxyphenyl)ethene: A Sterically Isolated Structural Model for Oxo-Surface Binding Domains

  摘要：

  The introduction of sterically isolating ortho-trialkylsilyl, -aryldialkylsilyl, and -diarylalkylsilyl substituents onto the structurally preorganized tetrakis(2-hydroxyphenyl)ethene ligand framework has been accomplished by a 4-fold retro-Brook rearrangement. Installation of the most sterically demanding silyl substituents required the development of an iterative procedure, involving successive double silylation/metalation/migration sequences without the isolation of intermediates. This system was designed to function as a soluble structural model for the planar binding domains of heterogeneous "oxo-surfaces" of silica and alumina supports.

  DOI：

  10.1021/ol801427w

文献信息

• <i>Ortho</i>-Silylated Derivatives of Tetrakis(2-hydroxyphenyl)ethene: A Sterically Isolated Structural Model for Oxo-Surface Binding Domains
  作者：Mee-Kyung Chung、Owen C. Lightbody、Jeffrey M. Stryker

  DOI：10.1021/ol801427w

  日期：2008.9.1

  The introduction of sterically isolating ortho-trialkylsilyl, -aryldialkylsilyl, and -diarylalkylsilyl substituents onto the structurally preorganized tetrakis(2-hydroxyphenyl)ethene ligand framework has been accomplished by a 4-fold retro-Brook rearrangement. Installation of the most sterically demanding silyl substituents required the development of an iterative procedure, involving successive double silylation/metalation/migration sequences without the isolation of intermediates. This system was designed to function as a soluble structural model for the planar binding domains of heterogeneous "oxo-surfaces" of silica and alumina supports.