9-(2,2-Dimethylpropyl)-2,5,9,12-tetrazabicyclo[11.4.0]heptadeca-1(17),13,15-triene-5-carboxylic acid

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 9-(2,2-Dimethylpropyl)-2,5,9,12-tetrazabicyclo[11.4.0]heptadeca-1(17),13,15-triene-5-carboxylic acid
• 英文别名: 9-(2,2-dimethylpropyl)-2,5,9,12-tetrazabicyclo[11.4.0]heptadeca-1(17),13,15-triene-5-carboxylic acid
• 化学式: C₁₉H₃₂N₄O₂
• 分子量: 348.5
• InChiKey: OBNDSLONHRVXNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  67.8
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• TUMOR AND IMMUNE CELL IMAGING BASED ON PD-L1 EXPRESSION
  申请人：The Johns Hopkins University

  公开号：US20190314531A1

  公开（公告）日：2019-10-17

  The presently disclosed subject matter provides compositions, kits, and methods comprising imaging agents that can detect Programmed Death Ligand 1 (PD-L1). The presently disclosed imaging agents can be used to detect diseases and disorders, such as cancer, infection, and inflammation, in a subject.