N-(4-pentenyl)-N-pentylamine | 263247-59-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(4-pentenyl)-N-pentylamine
• 英文别名: N-pent-4-enylpentan-1-amine
• CAS: 263247-59-2
• 化学式: C₁₀H₂₁N
• 分子量: 155.283
• InChiKey: OSBKIPLBXLNNLE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  11
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-(4-pentenyl)-N-pentylamine 在 双(2-氧代-3-恶唑烷基)次磷酰氯 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 生成 [(2R)-1,5-dioxo-1-[pent-4-enyl(pentyl)amino]-5-phenylmethoxypentan-2-yl]azanium;2,2,2-trifluoroacetate
  参考文献：
  名称：

  Synthesis of a radiolabeled type A cholecystokinin receptor antagonist, (R)-N-pentyl-N-(4,5-di[3H]pentyl) N?-(3-quinolinoyl)glutamic acid amide

  摘要：

  A method for the preparation of a radiolabeled CCKA-specific antagonist, (R)-N-pentyl-N-(4, 5-di[H-3]pentyl) N-alpha-(3-quinolinoyl)glutamic acid amide, [H-3]-A-65186, is described. (R)-gamma-Benzyl-N-BOC-glutamic acid was coupled with N-(4-pentenyl)-N-pentylamine using BOPCl and TEA in dichloromethane to provide the corresponding amide. Deprotection of the alpha-amino moiety followed by coupling with 3-quinolinecarboxylic acid in the presence of EDCI, TEA, and HOBt in dichloromethane resulted in (R)-N-(4-pentenyl)-N-pentyl gamma-benzyl-N-alpha-(3-quinolinoyl)glutamic acid amide. Tritiation with concomitant hydrogenolysis of the benzyl ester proceeds smoothly to provide [H-3]-A-65186.

  DOI：

  10.1002/(sici)1099-1344(200001)43:1<77::aid-jlcr292>3.0.co;2-v
• 作为产物：
  描述：

  4-戊烯醛 、 1-氨基戊烷 在 盐酸 、 3 A molecular sieve 、 sodium cyanoborohydride 作用下， 以 甲醇 为溶剂， 反应 72.0h， 以40%的产率得到N-(4-pentenyl)-N-pentylamine
  参考文献：
  名称：

  Synthesis of a radiolabeled type A cholecystokinin receptor antagonist, (R)-N-pentyl-N-(4,5-di[3H]pentyl) N?-(3-quinolinoyl)glutamic acid amide

  摘要：

  A method for the preparation of a radiolabeled CCKA-specific antagonist, (R)-N-pentyl-N-(4, 5-di[H-3]pentyl) N-alpha-(3-quinolinoyl)glutamic acid amide, [H-3]-A-65186, is described. (R)-gamma-Benzyl-N-BOC-glutamic acid was coupled with N-(4-pentenyl)-N-pentylamine using BOPCl and TEA in dichloromethane to provide the corresponding amide. Deprotection of the alpha-amino moiety followed by coupling with 3-quinolinecarboxylic acid in the presence of EDCI, TEA, and HOBt in dichloromethane resulted in (R)-N-(4-pentenyl)-N-pentyl gamma-benzyl-N-alpha-(3-quinolinoyl)glutamic acid amide. Tritiation with concomitant hydrogenolysis of the benzyl ester proceeds smoothly to provide [H-3]-A-65186.

  DOI：

  10.1002/(sici)1099-1344(200001)43:1<77::aid-jlcr292>3.0.co;2-v

文献信息

• QUATERNARY HETEROATOM CONTAINING COMPOUNDS
  申请人：California Institute of Technology

  公开号：EP3712140A1

  公开（公告）日：2020-09-23

  A compound useful for the preparation of building blocks for the manufacture of various compounds is represented by Formula 2a:

  一种可用于制备用于制造各种化合物的构筑模块的化合物由式 2a 表示：
• Home care compositions
  申请人：COLGATE-PALMOLIVE COMPANY

  公开号：US11008533B2

  公开（公告）日：2021-05-18

  Described herein are fabric care compositions comprising an esterquat, and a carbodiimide; along with methods of making and using same.

  本文描述了由酯奎特和碳化二亚胺组成的织物护理组合物，以及制造和使用该组合物的方法。
• HOME CARE COMPOSITIONS
  申请人：Colgate-Palmolive Company

  公开号：EP3884019A1

  公开（公告）日：2021-09-29
• US4874875A
  申请人：——

  公开号：US4874875A

  公开（公告）日：1989-10-17
• [EN] HOME CARE COMPOSITIONS<br/>[FR] COMPOSITIONS D'ENTRETIEN
  申请人：COLGATE PALMOLIVE CO

  公开号：WO2020139335A1

  公开（公告）日：2020-07-02

  Described herein are fabric care compositions comprising an esterquat, and a carbodiimide.