7-Methyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯并嘧啶类
• 英文名称: 7-Methyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione
• 英文别名: 7-methyl-1H-pyrrolo[2,3-d]pyrimidine-2,4-dione
• 化学式: C₇H₇N₃O₂
• 分子量: 165.15
• InChiKey: NKCKSKFBUCXXMA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  63.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• CATALYSTS FOR EPOXIDE CARBONYLATION
  申请人：Novomer, Inc.

  公开号：US20170080409A1

  公开（公告）日：2017-03-23

  The present invention encompasses catalysts for the carbonylation of heterocycles such as ethylene oxide, as well as methods for their use. The catalysts feature Lewis acidic metal complexes having one or more tethered metal-coordinating groups in combination with at least one metal carbonyl species. In preferred embodiments, the inventive catalysts have improved stability when subjected to product separation conditions in continuous ethylene oxide carbonylation processes.
• MOLECULAR WIRES FOR DETECTING A BIOLOGICAL OR CHEMICAL ENTITY OR EVENT
  申请人：VELANIDI TECHNOLOGIES LLC

  公开号：US20210341473A1

  公开（公告）日：2021-11-04

  Enantiomeric pairs of molecular wires comprised of oligomeric nucleic acids, wherein the oligomers of each wire possess identical nucleobase pair sequences and thus identical conductivity as between wires, are constructed and used to sense biological or chemical entities of interest at the cellular or molecular level. The oligomeric molecular wires conduct voltage inputs to sensing subsystem integrated circuitry, either from an electrostatic potential arising from a targeting agent (i.e., a capture agent) binding to an intended biological or chemical target molecule, or from an electrostatic potential associated with a reference molecule that has non-specific interactions with the environment. The chirality of the oligomers imparts selectivity to either the targeting agent or the reference molecule during assembly of the sensing subsystem.