2-[[4-[[(6R)-2-amino-4-oxo-5,6,7,8-tetrahydro-3H-pteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid;(2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: 2-[[4-[[(6R)-2-amino-4-oxo-5,6,7,8-tetrahydro-3H-pteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid;(2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal
• 化学式: C25H36N8O11
• 分子量: 624.6
• InChiKey: TWWDNDGQDXTUKV-MZSUGJMXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.69
• 重原子数：
  44
• 可旋转键数：
  14
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  331
• 氢给体数：
  13
• 氢受体数：
  15

文献信息

• [EN] FOLATES, COMPOSITIONS AND USES THEREOF<br/>[FR] FOLATES, COMPOSITIONS ET UTILISATIONS ASSOCIÉES
  申请人：GNOSIS SPA

  公开号：WO2009103334A1

  公开（公告）日：2009-08-27

  The present invention relates to folates, compositions and uses thereof; In particular, this invention describes a crystalline or amorphous compound which is a substituted or unsubstituted folate or a reduced folate, or the natural or unnatural isomers thereof, of at least one organic base, as well as compositions and uses thereof. The compounds of the invention show a long lasting stability as well as a peculiarly high water-solubility.

  本发明涉及叶酸、其组合物和用途；具体而言，本发明描述了一种晶体或非晶体化合物，该化合物是一种取代或未取代的叶酸或还原叶酸，或其天然或非天然异构体，至少含有一种有机碱基，以及其组合物和用途。本发明的化合物表现出长期稳定性以及特别高的水溶性。
• FOLATES, COMPOSITIONS AND USES THEREOF
  申请人：Gnosis S.p.A.

  公开号：EP2245032B1

  公开（公告）日：2015-03-25
• COMPOSITIONS, KITS AND METHODS FOR NUTRITION SUPPLEMENTATION
  申请人：CHEMO S.A. FRANCE

  公开号：US20140023751A1

  公开（公告）日：2014-01-23

  The present invention relates to compositions, kits and methods for the administration of various vitamin, mineral and nutrient compositions, and in a specific embodiment, the compositions, kits and methods may utilize or include twelve carbon chain fatty acids and/or twelve carbon chain acylglycerols, vitamin D, iodine, vitamin B1, vitamin B6, vitamin B12, vitamin B2, vitamin B9, vitamin B3, vitamin E, vitamin A, vitamin C, iron, zinc, copper, magnesium, omega 3 fatty acids and one or more pharmaceutically acceptable carriers.
• [EN] COMPOSITIONS, KITS AND METHODS FOR NUTRITIONAL SUPPLEMENTATION WITH TWELVE CARBON CHAIN FATTY ACIDS AND TWELVE CARBON CHAIN ACYLGLYCEROLS<br/>[FR] COMPOSITIONS, KITS ET MÉTHODES DE SUPPLÉMENTATION ALIMENTAIRE AVEC DES ACIDES GRAS À DOUZE ATOMES DE CARBONE ET DES ACYLGLYCÉROLS À DOUZE ATOMES DE CARBONE
  申请人：CHEMO S A FRANCE

  公开号：WO2013049519A2

  公开（公告）日：2013-04-04

  The present invention relates to compositions, kits and methods for the administration of compositions and kits for supplementation with twelve carbon chain fatty acids or twelve carbon chain acylglycerols; and specifically for the supplementation with twelve carbon chain fatty acids such as lauric acid and twelve carbon chain acylglycerols such as monolaurin; and specifically for the co-supplementation with other vitamins, minerals and nutrients.