7-Methoxy-3,5-dimethyl-1-benzothiophene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 7-Methoxy-3,5-dimethyl-1-benzothiophene
• 英文别名: 7-methoxy-3,5-dimethyl-1-benzothiophene
• 化学式: C₁₁H₁₂OS
• 分子量: 192.28
• InChiKey: VVYQAFKCWVXCNK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  37.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Substituted pyrrolo[2,1-f][1,2,4]triazines as FGFR inhibitors
  申请人：CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.

  公开号：US11236094B2

  公开（公告）日：2022-02-01

  Provided is a FGFR inhibitor, designating a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. Also provided is the application of a drug for treating solid tumors, such as FGFR related diseases.

  提供了一种 FGFR 抑制剂，指定由式 (I) 代表的化合物或其药学上可接受的盐。还提供了一种用于治疗实体瘤（如 FGFR 相关疾病）的药物。
• FGFR INHIBITOR AND MEDICAL APPLICATION THEREOF
  申请人：CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.

  公开号：US20200207773A1

  公开（公告）日：2020-07-02

  Provided is a FGFR inhibitor, designating a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. Also provided is the application of a drug for treating solid tumors, such as FGFR related diseases.
• PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE
  申请人：Bayer Pharma Aktiengesellschaft

  公开号：US20200339606A1

  公开（公告）日：2020-10-29

  A process for preparing the benzothiophen-2-yl boronate of formula (VI) which serves as an intermediate for production of medicaments and for production of medicaments for treatment and/or prophylaxis of proliferative disorders, such as cancer and tumor diseases.