申请人:Biomatrica, Inc.
公开号:EP3249054A1
公开(公告)日:2017-11-29
Described herein are stabilized polymerase compositions comprising a polymerase and an polymerase stabilizing agent, such as a non-detergent zwitterionic stabilizer or a cationic ester disclosed, for use in nucleic acid amplification or nucleic acid sequencing. Compositions are provided for the stabilization of one or more polymerases in a single stabilized liquid formulation. Also disclosed are methods for making and using stabilized polymerase compositions and kits for nucleic acid amplification and sequencing comprising the stabilized polymerase compositions provided.
本文描述的是用于核酸扩增或核酸测序的稳定聚合酶组合物,其中包含聚合酶和聚合酶稳定剂,例如所披露的非去垢齐聚物稳定剂或阳离子酯。所提供的组合物用于在单一稳定液体制剂中稳定一种或多种聚合酶。还公开了制造和使用稳定聚合酶组合物的方法,以及包含所提供的稳定聚合酶组合物的核酸扩增和测序试剂盒。