7-Phenyl-5-(4-sulfoanilino)benzo[a]phenazin-7-ium-3-sulfonic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 7-Phenyl-5-(4-sulfoanilino)benzo[a]phenazin-7-ium-3-sulfonic acid
• 化学式: C28H20N3O6S2+
• 分子量: 558.6
• InChiKey: IBIWIZFYQXMEJP-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  39
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  154
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• Light emission modifiers and their uses in nucleic acid detection, amplification and analysis
  申请人：Gupta P. Amar

  公开号：US20070020664A1

  公开（公告）日：2007-01-25

  The present invention relates to methods and reagents for modifying the emission of light from labeled nucleic acids for the purpose of real time detection, analysis, and quantitation of nucleic acid sequences, e.g., using singly labeled probes. These methods and reagents exploit advantageous properties of thiazine dyes and diazine dyes. Furthermore, the use of these light emission modifiers in background reduction, nucleic acid duplex stabilization and other uses is also described. Related kits, reaction mixtures and integrated systems are described.
• Light Emission Modifiers and Their Uses in Nucleic Acid Detection, Amplification and Analysis
  申请人：Gupta Amar P.

  公开号：US20100015598A1

  公开（公告）日：2010-01-21

  The present invention relates to methods and reagents for modifying the emission of light from labeled nucleic acids for the purpose of real time detection, analysis, and quantitation of nucleic acid sequences, e.g., using singly labeled probes. These methods and reagents exploit advantageous properties of thiazine dyes and diazine dyes. Furthermore, the use of these light emission modifiers in background reduction, nucleic acid duplex stabilization and other uses is also described. Related kits, reaction mixtures and integrated systems are described.
• DETECTION OF TARGET VARIANTS USING A FLUORESCENT LABEL AND A SOLUBLE QUENCHER
  申请人：Will Stephen Gordon

  公开号：US20100124744A1

  公开（公告）日：2010-05-20

  Methods, reaction mixtures and systems for detecting the presence or absence of a target nucleic acid variant from a selection of possible variants is described.
• US7964598B2
  申请人：——

  公开号：US7964598B2

  公开（公告）日：2011-06-21
• US8658366B2
  申请人：——

  公开号：US8658366B2

  公开（公告）日：2014-02-25