(8R,9S,10S,13S,14S)-13-methyl-1,2,4,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (8R,9S,10S,13S,14S)-13-methyl-1,2,4,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione
• 化学式: C₁₈H₂₄O₂
• 分子量: 272.4
• InChiKey: WELNRNVZXWUOGT-JLOCXQCDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS
  申请人：INITIUM INNOVATIONS, INC.

  公开号：US20190298646A1

  公开（公告）日：2019-10-03

  Disclosed herein are sustained release compositions of anti-inflammatory agents and methods of use. In some embodiments, the biodegradable sustained release compositions comprise an effective amount of an anti-inflammatory agent selected from a steroid, ta calcineurin inhibitor, a PDE4 inhibitor, an antibiotic, and combinations thereof. Also disclosed herein are methods to treat an inflammatory condition in a subject by administering a biodegradable sustained release compositions of the anti-inflammatory agent.
• [EN] TASTE-MASKED DOSAGE FORMS<br/>[FR] FORMES POSOLOGIQUES À GOÛT MASQUÉ
  申请人：BAINS KENWALJIT SINGH

  公开号：WO2020061584A1

  公开（公告）日：2020-03-26

  Sublingual dosage forms comprising a bitter active ingredient (including sildenafil, tadalafil, tetrahydrocannabinol, and cannabidiol) and a bitterness reducing agent are described. Methods of treating sexual dysfunction by administering the sublingual dosage form to an individual in need thereof are also described.