苯二醇,单乙酸酯 | 151195-78-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 苯二醇,单乙酸酯
• 英文名称: Acetic acid;benzene-1,2-diol
• CAS: 151195-78-7
• 化学式: C8H10O4
• 分子量: 170.16
• InChiKey: GZZSZTGDQJSEQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.19
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES
  申请人：Wagner Barbara

  公开号：US20120230925A1

  公开（公告）日：2012-09-13

  Disclosed is the use of benzotropolone derivatives of formula (1), wherein R 1 , R 2 and R 7 independently from each other are hydrogen; C 1 -C 3 alkyl; or COR 8 ; R 3 is hydrogen; or COOR 9 R 4 is hydrogen; or C 1 -C 3 alkyl; R 5 is hydrogen; hydroxy; C 1 -C 3 -alkoxy; or -0-(CO)—R 10 ; R 6 is hydrogen; C 1 -C 3 alkyl; or COR 8 ; or R 5 and R 6 together may form a five or six membered ring; or R 6 and R 7 together form a five or six membered ring; and R 8 , R 9 , R 10 independently of each other are C 1 -C 30 alkyl; for protecting body-care and household products from photolytic and oxidative degradation.

  本发明涉及一种使用化学式（1）中的苯并三酮衍生物的方法，其中R1、R2和R7分别独立地为氢原子；C1-C3烷基；或COR8；R3为氢原子；或COOR9；R4为氢原子；或C1-C3烷基；R5为氢原子；羟基；C1-C3-烷氧基；或-0-(CO)—R10；R6为氢原子；C1-C3烷基；或COR8；或R5和R6可以共同形成五元或六元环；或R6和R7可以共同形成五元或六元环；且R8、R9、R10分别独立地为C1-C30烷基；用于保护身体护理和家用产品免受光解和氧化降解的方法。
• Diazotype compositions and materials
  申请人：Andrews Paper and Chemical Co., Inc.

  公开号：EP0122523A2

  公开（公告）日：1984-10-24

  The use of soluble methylol compounds from primary or secondary amines or ammonia with formaldehyde in diazotypes improves solution compatibility and prevents coupler migration upon storage of diazotype materials. The methylol compounds may be reacted with couplers separately or added to the coating preparations.

  在重氮涂料中使用由伯胺、仲胺或氨与甲醛组成的可溶性甲醇化合物，可提高溶液的相容性，并防止重氮涂料储存时耦合剂迁移。甲醇化合物可以单独与耦合剂反应，也可以添加到涂层制剂中。
• Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia
  申请人：Bristol-Myers Squibb Company

  公开号：EP0476493A1

  公开（公告）日：1992-03-25

  This invention relates to structurally novel acyclic tocotrienol analogs, which are useful for cholesterol/lipid lowering in cases of hypercholesterolemia and hyperlipidemia, and for atherosclerosis. Also provided are pharmaceutical compositions and a method of use employing those compositions.

  本发明涉及结构新颖的无环生育三烯酚类似物，可用于降低高胆固醇血症和高血脂症患者的胆固醇/血脂，以及治疗动脉粥样硬化。本发明还提供了药物组合物和使用这些组合物的方法。
• Acyclic Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia
  申请人：Bristol-Myers Squibb Company

  公开号：EP0571928A1

  公开（公告）日：1993-12-01

  This invention relates to structurally novel acyclic tocotrienol analogs, which are useful for cholesterol/lipid lowering in cases of hypercholesterolemia and hyperlipidemia, and for atherosclerosis. Also provided are pharmaceutical compositions and a method of use employing those compositions.

  本发明涉及结构新颖的无环生育三烯酚类似物，可用于降低高胆固醇血症和高血脂症患者的胆固醇/血脂，以及治疗动脉粥样硬化。本发明还提供了药物组合物和使用这些组合物的方法。
• Acyclic isoprenoid ether derivatives as chemotherapeutics
  申请人：——

  公开号：US20020045584A1

  公开（公告）日：2002-04-18

  A method of and compositions for suppressing the growth of tumor cells in a patient are disclosed. In one embodiment, the method comprises treating the patient with an effective amount of an isoprenoid ether-linked compound, wherein the isoprenoid ether-linked compound comprises a first acyclic isoprenoid molecule linked via an ether linkage to a second molecule, wherein the second molecule can suppress tumor formation.

  本发明公开了一种抑制患者体内肿瘤细胞生长的方法和组合物。在一个实施方案中，该方法包括用有效量的异戊二烯醚键化合物治疗患者，其中异戊二烯醚键化合物包括通过醚键与第二分子连接的第一无环异戊二烯分子，其中第二分子可抑制肿瘤形成。