2,2-Dioxo-2,3,5,6,7,8-hexahydro-2λ⁶-benzo[e][1,2,3]oxathiazin-4-one | 33666-07-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: 2,2-Dioxo-2,3,5,6,7,8-hexahydro-2λ⁶-benzo[e][1,2,3]oxathiazin-4-one
• 英文别名: 5,6,7,8-Tetrahydro-2H-1,2lambda~6~,3-benzoxathiazine-2,2,4(3H)-trione；2,2-dioxo-5,6,7,8-tetrahydro-1,2λ6,3-benzoxathiazin-4-one
• CAS: 33666-07-8
• 化学式: C₇H₉NO₄S
• 分子量: 203.219
• InChiKey: NRWXRQXRXNBNRC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  80.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,2-Dioxo-2,3,5,6,7,8-hexahydro-2λ⁶-benzo[e][1,2,3]oxathiazin-4-one 在 五氯化磷 作用下， 以 四氯化碳 为溶剂， 以75%的产率得到4-Chloro-5,6,7,8-tetrahydro-benzo[e][1,2,3]oxathiazine 2,2-dioxide
  参考文献：
  名称：

  Sander, Juergen; Clauss, Karl, Angewandte Chemie, 1980, vol. 92, # 2, p. 138 - 139

  摘要：

  DOI：

文献信息

• MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH
  申请人：Tachdjian Catherine

  公开号：US20080306053A1

  公开（公告）日：2008-12-11

  The present invention provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors as well as modifiers capable of modulating chemosensory receptors and their ligands.

  本发明提供了用于识别化学感受受体及其配体的修饰因子的筛选方法，例如，通过确定测试实体是否适合与化学感受受体的捕蝇草结构域内的一个或多个相互作用位点发生相互作用，以及能够调节化学感受受体及其配体的修饰因子。
• Antimicrobial Devices and Compositions
  申请人：Karandikar Bhalchandra M.

  公开号：US20090035342A1

  公开（公告）日：2009-02-05

  The present invention comprises methods and compositions for antimicrobial devices comprising metal containing compositions which are resistant to heat and light discoloration. The metal containing compositions may comprise salts or complexes of silver, copper or zinc. In one aspect the compositions comprise silver salts. In another aspect, the compositions comprise silver complexes. In one aspect, the metal salts may comprise metal salts of saccharin, acesulfame, long chain fatty acids, and alkyl dicarboxylic acids. The compositions further comprise polymers which form salts or complexes with silver, copper or zinc. The methods of the present invention comprise treating devices with the metal containing compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices. The present invention further comprises treatment of humans and animals with the antimicrobial devices described herein.

  本发明涉及一种包括金属含量组合物的抗菌装置的方法和组合物，该组合物对热和光变色具有抗性。金属含量组合物可以包括银、铜或锌的盐或络合物。在一方面，组合物包括银盐。在另一方面，组合物包括银络合物。在一方面，金属盐可以包括糖精盐、乙酰糖胺盐、长链脂肪酸盐和烷基二羧酸盐。该组合物进一步包括与银、铜或锌形成盐或络合物的聚合物。本发明的方法包括使用金属含量组合物处理装置，包括但不限于编织伤口护理材料、导管、患者护理设备和胶原蛋白基质等装置。本发明还包括使用上述抗菌装置治疗人类和动物的方法。
• Methods and compositions for metal nanoparticle treated surfaces
  申请人：Avent, Inc.

  公开号：EP2859961A2

  公开（公告）日：2015-04-15

  Disclosed is method of making metal nanoparticles comprising, a) adding in no particular order, an aqueous solution of a stabilizing agent solution, an anionic donating solution and a soluble metal salt solution, and b) adding a reducing solution. Also disclosed are metal nanoparticles made by the method.

  所公开的金属纳米粒子的制造方法包括 a) 不按特定顺序加入稳定剂溶液、阴离子捐献溶液和可溶性金属盐溶液的水溶液，以及 b) 加入还原溶液。 还公开了用该方法制得的金属纳米粒子。
• Antimicrobial devices and compositions
  申请人：Karandikar Bhalchandra M.

  公开号：US10251392B2

  公开（公告）日：2019-04-09

  The present invention comprises methods and compositions for antimicrobial devices comprising metal containing compositions which are resistant to heat and light discoloration. The metal containing compositions may comprise salts or complexes of silver, copper or zinc. In one aspect the compositions comprise silver salts. In another aspect, the compositions comprise silver complexes. In one aspect, the metal salts may comprise metal salts of saccharin, acesulfame, long chain fatty acids, and alkyl dicarboxylic acids. The compositions further comprise polymers which form salts or complexes with silver, copper or zinc. The methods of the present invention comprise treating devices with the metal containing compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices. The present invention further comprises treatment of humans and animals with the antimicrobial devices described herein.

  本发明包括用于抗菌装置的方法和组合物，其中包含耐热和耐光变色的含金属组合物。含金属的组合物可包括银、铜或锌的盐或络合物。一方面，组合物包含银盐。另一方面，组合物还包括银络合物。一方面，金属盐可包括糖精、安赛蜜、长链脂肪酸和烷基二羧酸的金属盐。组合物还包括与银、铜或锌形成盐或络合物的聚合物。本发明的方法包括用含金属的组合物处理设备，包括但不限于编织伤口护理材料、导管、病人护理设备和胶原蛋白基质等设备。本发明还包括用本文所述的抗菌装置处理人和动物。
• METHODS FOR FORMING SILVER-NANOPARTICLE TREATED SURFACES
  申请人：Kimberly-Clark Worldwide, Inc.

  公开号：EP1991365B1

  公开（公告）日：2014-12-24