1,3-di-n-propylacetamidine | 106500-92-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,3-di-n-propylacetamidine
• 英文别名: N,N'-di-n-propylacetamidine；N,N'-dipropylethanimidamide
• CAS: 106500-92-9
• 化学式: C₈H₁₈N₂
• 分子量: 142.244
• InChiKey: GQOFLGSFJGEWAF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  24.4
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  copper(l) chloride 、 1,3-di-n-propylacetamidine 在 methyllithium 作用下， 以 乙醚 为溶剂， 以83%的产率得到copper(I) N,N'-di-n-propylacetamidinate
  参考文献：
  名称：

  Synthesis and Characterization of Copper(I) Amidinates as Precursors for Atomic Layer Deposition (ALD) of Copper Metal

  摘要：

  A series of copper(I) amidinates of the general type [(R ' NC(R)NR '')Cu](2) (R ' and R '' = n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl, tert-butyl; R = methyl, n-butyl) have been synthesized and characterized. These compounds are planar dimers, bridged by nearly linear N-Cu-N bonds. Their properties (volatility, low melting point, high thermal stability, and self-limited surface reactivity) are well-suited for atomic layer deposition (ALD) of copper metal films that are pure, highly conductive, conformal, and strongly adherent to substrates.

  DOI：

  10.1021/ic048492u
• 作为产物：
  描述：

  正丙胺 、 乙基乙酰亚胺盐酸盐 生成 1,3-di-n-propylacetamidine
  参考文献：
  名称：

  Pinner, Die Imidoaether und ihre Derivate ,S.113

  摘要：

  DOI：

文献信息

• Samarium diiodide promoted synthesis of N,N ′-disubstituted amidines
  作者：Fan Xu、Jianhua Sun、Qi Shen

  DOI：10.1016/s0040-4039(02)00129-6

  日期：2002.3

  An efficient one-step preparation of an N,N′-disubstituted amidine by the direct nucleophilic addition of an amine to the parent nitrile using catalytic amounts of SmI2 under relatively mild conditions is developed. Alkyl, benzyl and aryl amidines are prepared in moderate to good yields from the corresponding nitriles.

  通过在相对温和的条件下使用催化量的SmI 2将胺直接亲核加成到母体腈中，开发了一种有效的一步制备N，N'-二取代am的方法。从相应的腈以中等至良好的产率制备烷基，苄基和芳基am。
• Use of lanthanide(III) ions as catalysts for the reactions of amines with nitriles
  作者：John H. Forsberg、Vincent T. Spaziano、Trichey M. Balasubramanian、Gordon K. Liu、Steven A. Kinsley、Charles A. Duckworth、John J. Poteruca、Paul S. Brown、Judith L. Miller

  DOI：10.1021/jo00382a009

  日期：1987.3
• Platinum catalysed hydrolytic amidation of unactivated nitriles
  作者：Christopher J Cobley、Marco van den Heuvel、Abdelilah Abbadi、Johannes G de Vries

  DOI：10.1016/s0040-4039(00)00181-7

  日期：2000.4

  The platinum(II) complex, [(Me2PO .. H .. OPMe2)PtH(PMe2OH)], efficiently catalyses the direct conversion of unactivated nitriles to N-substituted amides with both primary and secondary amines. Possible mechanisms for this reaction are discussed and evidence for initial amidine formation is reported. Isolated yields vary from 51-89%. (C) 2000 Elsevier Science Ltd. All rights reserved.
• Pinner, Die Imidoaether und ihre Derivate <Berlin 1892>,S.113
  作者：Pinner

  DOI：——

  日期：——
• Arens; Rix, 1954, vol. 57, p. 275,277
  作者：Arens、Rix

  DOI：——

  日期：——