3-oxido-2H-phthalazin-3-ium-1-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 3-oxido-2H-phthalazin-3-ium-1-one
• 化学式: C8H6N2O2
• 分子量: 162.15
• InChiKey: UWJTXGCDYUBELR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  57.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Thermally developable photographic elements
  申请人：Imation Corp.

  公开号：EP0533007B1

  公开（公告）日：1998-06-17
• COMPOSITIONS AND NETHODS FOR TREATING BRAIN DYSFUNCTION
  申请人：Bach Pharma, Inc.

  公开号：EP3397257A1

  公开（公告）日：2018-11-07
• JPH11230909A
  申请人：——

  公开号：JPH11230909A

  公开（公告）日：1999-08-27
• [EN] COMPOSITIONS AND NETHODS FOR TREATING BRAIN DYSFUNCTION<br/>[FR] COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT D'UN DYSFONCTIONNEMENT CÉRÉBRAL
  申请人：BACH PHARMA INC

  公开号：WO2017117586A1

  公开（公告）日：2017-07-06

  The present invention relates to compositions that can be used, for example, in methods of treating medical conditions and symptoms associated with brain dysfunction, including but not limited to Gulf War illness (GWI), multiple chemical sensitivity (MCS), cognitive dysfunction (CD), multiple sclerosis (MS), and neurological disorders such as amyotrophic lateral sclerosis (ALS). in various embodiments, the compositions of the invention, which can. be administered or prepared as a medicament for use in the treatment methods described herein, are phthalazinediones or pharmaceutically acceptable salts thereof. As described further below, the phthalazinedione can be 5-amino-2,3-dihydro-1;4-phthala2:inedion.e; an analog or variant thereof; or a salt of the specified compound, the analog, or the variant. The compounds described herein can be formulated as diagnostic or pharmaceutical compositions, and the invention features kits including one or more of these compounds.