6-Hydroxy-4-methyl-pteridin | 16041-28-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: 6-Hydroxy-4-methyl-pteridin
• 英文别名: 4-methyl-5H-pteridin-6-one
• CAS: 16041-28-4
• 化学式: C₇H₆N₄O
• 分子量: 162.151
• InChiKey: YNFBWEAWNVAYFG-UHFFFAOYSA-N

物化性质

• 密度：
  1.56±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  67.2
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• AMINO ACID LIPIDS AND USES THEREOF
  申请人：Quay Steven C.

  公开号：US20080317839A1

  公开（公告）日：2008-12-25

  This disclosure provides a range of amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.

  这份披露提供了一系列氨基酸脂类化合物和组合物，可用于药物传递、治疗、诊断和治疗疾病和病况。这些氨基酸脂类化合物和组合物可用于将各种药剂如核酸治疗剂传递到细胞、组织、器官和受试者中。
• Amino acid lipids and uses thereof
  申请人：Quay Steven C.

  公开号：US20110177160A1

  公开（公告）日：2011-07-21

  This disclosure provides a range of amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.

  本文披露了一系列氨基酸脂类化合物和组合物，可用于药物传递、治疗、疾病和病况的诊断和治疗。氨基酸脂类化合物和组合物可用于将各种药剂如核酸治疗剂传递至细胞、组织、器官和受试者。
• TYROSINE-BASED LIPIDS FOR DELIVERY OF THERAPEUTICS
  申请人：Marina Biotech, Inc.

  公开号：US20160206739A1

  公开（公告）日：2016-07-21

  This disclosure provides a range of tyrosine amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.

  本披露提供了一系列酪氨酸氨基酸脂类化合物和组合物，可用于药物输送、治疗以及疾病和病症的诊断和治疗。这些氨基酸脂类化合物和组合物可用于将各种药剂如核酸治疗剂输送至细胞、组织、器官和受试者。
• Composition and method for array hybridization
  申请人：Agilent Technologies, Inc.

  公开号：EP1702990A1

  公开（公告）日：2006-09-20

  The present disclosure provides a system, composition, and method for hybridizing a microarray. The composition includes a superwetting agent. The method includes contacting the microarray with an aqueous mixture including the superwetting agent.

  本公开提供了一种用于芯片杂交的系统、组合物和方法。组合物包括超润湿剂。该方法包括将微阵列与包括超润湿剂的水性混合物接触。
• Fast hybridization for next generation sequencing target enrichment
  申请人：Agilent Technologies, Inc.

  公开号：EP2902504A1

  公开（公告）日：2015-08-05

  The present invention relates to compositions and methods of target enrichment or selection of nucleic acids using hybridization, which can be used in, e.g., next-generation sequencing.

  本发明涉及利用杂交对核酸进行靶向富集或选择的组合物和方法，可用于下一代测序等。