1,2-diphenylpropyl acetate | 32268-44-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1,2-diphenylpropyl acetate
• 英文别名: 1-Acetoxy-1,2-diphenyl-propan；1,2-Diphenyl-1-acetoxypropan
• CAS: 32268-44-3
• 化学式: C₁₇H₁₈O₂
• 分子量: 254.329
• InChiKey: MTECUCFYTJNMET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,2-diphenylpropyl acetate 在 甲醇 、 potassium hydroxide 作用下， 生成 (1S,2S)-1,2-二苯基丙烷-1-醇 、 (1S,2S)-1,2-二苯基丙烷-1-醇
  参考文献：
  名称：

  Alkene Oxyalkylation Enabled by Merging Rhenium Catalysis with Hypervalent Iodine(III) Reagents via Decarboxylation

  摘要：

  Rhenium-catalyzed oxyalkylation of alkenes is described, where hypervalent iodine(III) reagents derived from widely occurring aliphatic carboxylic acids were used as, for the first time, not only an oxygenation source but also an alkylation source via decarboxylation. The reaction also features a wide substrate scope, totally regiospecific difunctionalization, mild reaction conditions, and ready availability of both substrates. Mechanistic studies revealed a decarboxylation/radical-addition/cation-trapping cascade operating in the reaction.

  DOI：

  10.1021/ja410195j
• 作为产物：
  描述：

  (反式)-1,1'-(1,2-环丙烷二基)二苯 在 sodium tetrahydroborate 、 高氯酸 、 mercury(II) diacetate 、 sodium chloride 作用下， 生成 1,2-diphenylpropyl acetate 、 threo-1,2-diphenyl-1-acetoxypropane
  参考文献：
  名称：

  Bandaev, S. G.; Sychkova, L. D.; Hantschmann, A., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, p. 257 - 262

  摘要：

  DOI：

文献信息

• Bandaev, S. G.; Sabarov, Yu. S.; Hantschmann, A., Journal fur praktische Chemie (Leipzig 1954), 1980, vol. 322, # 4, p. 643 - 648
  作者：Bandaev, S. G.、Sabarov, Yu. S.、Hantschmann, A.、Weissenfels, M.

  DOI：——

  日期：——
• Alkene Oxyalkylation Enabled by Merging Rhenium Catalysis with Hypervalent Iodine(III) Reagents via Decarboxylation
  作者：Yin Wang、Lei Zhang、Yunhui Yang、Ping Zhang、Zhenting Du、Congyang Wang

  DOI：10.1021/ja410195j

  日期：2013.12.4

  Rhenium-catalyzed oxyalkylation of alkenes is described, where hypervalent iodine(III) reagents derived from widely occurring aliphatic carboxylic acids were used as, for the first time, not only an oxygenation source but also an alkylation source via decarboxylation. The reaction also features a wide substrate scope, totally regiospecific difunctionalization, mild reaction conditions, and ready availability of both substrates. Mechanistic studies revealed a decarboxylation/radical-addition/cation-trapping cascade operating in the reaction.
• Bandaev, S. G.; Sychkova, L. D.; Hantschmann, A., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, p. 257 - 262
  作者：Bandaev, S. G.、Sychkova, L. D.、Hantschmann, A.、Shabarov, Yu. S.

  DOI：——

  日期：——