2-ethyl-2H-thiopyran | 75980-65-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫吡喃类
• 英文名称: 2-ethyl-2H-thiopyran
• CAS: 75980-65-3
• 化学式: C₇H₁₀S
• 分子量: 126.22
• InChiKey: GQGPAOVRSUWPSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Novel Inhibitors of Proliferation and Activation of Signal Transducer and Activator of Transcription (STATS)
  申请人：Priebe Waldemar

  公开号：US20110053992A1

  公开（公告）日：2011-03-03

  Pyridine compounds effective in modulation STAT3 and/or STAT5 activation are provided that are useful in the prevention and treatment of proliferative disease and conditions including cancer, inflammation and proliferative skin disorders.

  提供有效调节STAT3和/或STAT5激活的吡啶化合物，可用于预防和治疗增生性疾病和病症，包括癌症、炎症和增生性皮肤疾病。
• NOVEL INHIBITORS OF PROLIFERATION AND ACTIVATION OF SIGNAL TRANSDUCER AND ACTIVATORS OF TRANSCRIPTION (STATS)
  申请人：Priebe Waldemar

  公开号：US20120149738A1

  公开（公告）日：2012-06-14

  Pyridine compounds effective in modulation STAT3 and/or STAT5 activation are provided that are useful in the prevention and treatment of proliferative disease and conditions including cancer, inflammation and proliferative skin disorders.

  提供了能够有效调节STAT3和/或STAT5激活的吡啶化合物，可用于预防和治疗增生性疾病和病症，包括癌症、炎症和增生性皮肤疾病。
• Polymer catalyst transducers and use thereof in test kits for analytical methods
  申请人：MILES INC.

  公开号：EP0140322A2

  公开（公告）日：1985-05-08

  Polymer-catalyst tranducers and their use for detecting one or more constituents in a sample are disclosed. Changes in conductivity of the polymercatalyst transducers as a result of electron density changes are measured to provide an indication of a particular constituent present in the sample. Such conductivity changes can be measured using a conductivity meter. The polymer-catalyst tranducers are particularly useful for the determination of glucose in whole blood.

  本发明公开了聚合物催化剂诱导体及其用于检测样品中一种或多种成分的方法。通过测量电子密度变化引起的聚合物催化剂传感器电导率的变化，可以显示样品中存在的特定成分。这种电导率变化可以使用电导率仪进行测量。聚合物催化剂诱导体特别适用于测定全血中的葡萄糖。
• Methods of Treating Skin Disorders with Caffeic Acid Analogs
  申请人：Priebe Waldemar

  公开号：US20100152143A1

  公开（公告）日：2010-06-17

  Embodiments of the invention generally relate to pharmaceutical compositions containing at least one caffeic acid compound and methods for the topical treatment of proliferative and inflammatory skin disorders such as plaque psoriasis, atopic dermatitis, and other disorders. In some embodiments, the topical treatment includes applications of the pharmaceutical composition containing at least one caffeic acid compound or a mixture of caffeic acid compounds such as caffeic acid ester compounds, caffeic acid amide compounds, analogues thereof, derivatives thereof, salts thereof, or mixtures thereof. The pharmaceutical composition or topical dosage may contain the caffeic acid compound at a concentration by weight within a range from about 0.01% to about 20%, preferably, from about 0.1% to about 15%, preferably, from about 1% to about 10%, more preferably, from about 3% to about 7%, and more preferably, from about 4% to about 6%.
• COMPOUNDS FOR TREATMENT OF CELL PROLIFERATIVE DISEASES
  申请人：Priebe Waldemar

  公开号：US20110021805A1

  公开（公告）日：2011-01-27

  The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. Compounds of the present invention display significant potency as kinase inhibitors, cause the downregulation of c-myc, and inhibit the growth and survival of cancerous cell lines.