2-[(2,6-dimethyl-4H-pyran-4-ylidene)methyl]-3-methyl-1,3-benzothiazol-3-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 2-[(2,6-dimethyl-4H-pyran-4-ylidene)methyl]-3-methyl-1,3-benzothiazol-3-ium
• 英文别名: 2-[(2,6-dimethylpyran-4-ylidene)methyl]-3-methyl-1,3-benzothiazol-3-ium
• 化学式: C16H16NOS+
• 分子量: 270.4
• InChiKey: YFVRWYRQLXSZLE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  41.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Method and compounds for the fluorescent labelling of biomolecules and polymer particles
  申请人：Yarmoluk M. Sergey

  公开号：US20070184559A1

  公开（公告）日：2007-08-09

  Hence the invention concerns a method which can be used to provide a fluorescent label on bioorganic molecules carrying amino groups such as amino acids, proteins, pharmaceutical agents, antibodies, amino group-modified nucleotides and also polymers and polymer particles carrying amino groups by means of a chemical (covalent) binding. The method is based on the reaction of a pyrylium salt located on a fluorophore F with the amino group of a biomolecule or particle according to the described reaction equation. The method is selective, simple to carry out and results in high labelling yields. The spectral properties of the conjugates differ considerably from those of the starting compounds and their fluorescence quantum yields are often considerably increased.