N-pentafluorophenylnaphthalene-1-carboxamide | 541520-05-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-pentafluorophenylnaphthalene-1-carboxamide
• 英文别名: N-(2,3,4,5,6-pentafluorophenyl)naphthalene-1-carboxamide
• CAS: 541520-05-2
• 化学式: C₁₇H₈F₅NO
• 分子量: 337.249
• InChiKey: UZNUAGINYYVWHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N-pentafluorophenylnaphthalene-1-carboxamide 在 五氯化磷 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Fluorinated Bis(phenoxyketimine)titanium Complexes for the Living, Isoselective Polymerization of Propylene:  Multiblock Isotactic Polypropylene Copolymers via Sequential Monomer Addition

  摘要：

  A series of bis(phenoxyketimine)titanium dichloride complexes were synthesized and evaluated as catalysts for living, isoselective propylene polymerization upon activation with methylaluminoxane (MAO). Catalysts bearing phenoxyketimine ligands with different substituents at the ortho and para. positions of the phenolate ring and substituents at the ketimine carbon were investigated. The identity of the ketimine substituent had the largest effect on the activity and isoselectivity of propylene polymerization. Complex 12/MAO promoted the living, isoselective polymerization of propylene ([m(4)] = 0.73, alpha = 0.94). This catalyst system was used for the synthesis of a number of block copolymers featuring isotactic polypropylene semicrystalline blocks and poly(ethylene-co-propylene) amorphous blocks. Several triblock samples with varying block lengths, a pentablock, and a heptablock copolymer were synthesized. Mechanical testing has revealed that each is elastomeric with elongations at break between similar to 790-1000%.

  DOI：

  10.1021/ja077772g
• 作为产物：
  描述：

  1-萘甲酸 在 草酰氯 作用下， 以 甲苯 为溶剂， 反应 24.0h， 生成 N-pentafluorophenylnaphthalene-1-carboxamide
  参考文献：
  名称：

  配体促进的RhIII催化的苯甲酰胺具有广泛的二硫键范围的硫醇化作用

  摘要：

  已经开发了配体促进的Rh III催化苯甲酰胺的C（sp 2）-H活化/硫醇化。使用双齿单-N-保护的氨基酸配体导致了第一个由弱配位的直接酰胺基团指导的Rh III催化的芳基硫醇化反应的例子。该反应可耐受各种酰胺和二硫化物试剂。

  DOI：

  10.1002/anie.201903511

文献信息

• Selective annulation of benzamides with internal alkynes catalyzed by an electron-deficient rhodium catalyst
  作者：Ping Zhang、Wenju Chang、Hongyun Jiao、Yanshang Kang、Wenxuan Zhao、Peipei Cui、Yong Liang、Wei-Yin Sun、Yi Lu

  DOI：10.1016/j.cclet.2021.01.024

  日期：2021.5

  s with internal alkynes was successfully established under mild reaction conditions, with the assistance of Lewis acid silver salt. Particularly, electron-deficient benzamide substrates were smoothly transformed into the desired products in this catalytic system. The catalytic system showed a broad tolerance for different substituents on the aromatic rings or aryl, alkyl-substituted alkynes.

  在路易斯酸银盐的辅助下，在温和的反应条件下成功建立了电子缺陷[Cp E RhCl 2 ] 2催化的N-五氟苯基苯甲酰胺与内部炔烃的环化反应。尤其是，在该催化体系中，缺电子的苯甲酰胺底物可以平稳地转化为所需的产物。催化体系显示出对芳环或芳基，烷基取代的炔烃上不同取代基的宽容度。
• Divergent synthesis of aryl amines and dihydroquinazolinones via electrochemistry-enabled rhodium-catalyzed C–H functionalization
  作者：Yi-Kang Xing、Zhen-Hua Wang、Ping Fang、Cong Ma、Tian-Sheng Mei

  DOI：10.1007/s11426-023-1603-9

  日期：2023.10

  Electrochemistry-enabled rhodium-catalyzed C–H amination and amination cyclization of arene assisted by a weakly coordinating amide have been reported. Additionally, aryl amines and dihydroquinazolinones could be obtained selectively by controlling the electric current. Mechanistic studies suggested that the amination reaction likely involves an electrochemical oxidation-induced reductive elimination

  已经报道了在弱配位酰胺的辅助下电化学启用的铑催化的芳烃的 C-H 胺化和胺化环化。此外，通过控制电流可以选择性地获得芳基胺和二氢喹唑啉酮。机理研究表明，胺化反应可能涉及电化学氧化诱导的高价铑中间体的还原消除，这导致胺化反应甚至在室温下顺利进行。
• NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME
  申请人：KABUSHIKIKAISHA UENO SEIYAKU OYO KENKYUJO

  公开号：EP0765858A1

  公开（公告）日：1997-04-02

  A naphthol derivative represented by the general formula (I) [wherein Y and Y' indicate -(CONH)n-X or -COR; X is a phenyl group, a naphthyl group, an anthraquinonyl group, a benzimidazolonyl group or a carbazolyl group; R is a hydroxyl group, an alkoxy group having 1 to 6 carbon atoms, a halogen atom, a benzyloxy group, a phenyloxy group or a phenacyloxy group; R2 is a hydrogen atom, an alkaline metal, an alkyl group having 1 to 6 carbon atoms, an acyl group having 1 to 6 carbon atoms or a phenylalkyl group; Z is a group selected from the group consisting of a hydrogen atom, a halogen atom, a nitro group, a nitroso group and an amino group (Z may be substituted on any ring of the naphthalene ring); and n is an integer of 1 or 2; provided that R2 and Z do not simultaneously indicate a hydrogen atom when both R simultaneously indicate a hydroxyl group], and a process for producing the same. This naphthol derivative can be used as raw materials for synthesis, such as dyes, pigments, photosensitive materials and the like.

  通式(I)代表的萘酚衍生物[其中Y和Y'表示-(CONH)n-X或-COR；X是苯基、萘基、蒽醌基、苯并咪唑基或咔唑基；R 是羟基、1 至 6 个碳原子的烷氧基、卤素原子、苄氧基、苯氧基或苯乙氧基； R2 是氢原子、碱金属、1 至 6 个碳原子的烷基、1 至 6 个碳原子的酰基或苯基烷基；Z 是选自氢原子、卤素原子、硝基、亚硝基和氨基（Z 可在萘环的任何环上被取代）的基团；以及 n 是 1 或 2 的整数；条件是当两个 R 同时表示羟基时，R2 和 Z 不同时表示氢原子]，以及生产该衍生物的工艺。这种萘酚衍生物可用作染料、颜料、感光材料等合成原料。
• US5786523A
  申请人：——

  公开号：US5786523A

  公开（公告）日：1998-07-28
• US6252104B1
  申请人：——

  公开号：US6252104B1

  公开（公告）日：2001-06-26