3,3'-dioctadecyl-2,2'-thiacarbocyanine | 47896-50-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 3,3'-dioctadecyl-2,2'-thiacarbocyanine
• 英文别名: 1,3-bis-(3-octadecyl-benzothiazol-2-yl)-trimethinium；3-octadecyl-2-[3-(3-octadecyl-3H-benzothiazol-2-ylidene)-propenyl]-benzothiazolium；(2Z)-3-octadecyl-2-[(E)-3-(3-octadecyl-1,3-benzothiazol-3-ium-2-yl)prop-2-enylidene]-1,3-benzothiazole
• CAS: 47896-50-4
• 化学式: C₅₃H₈₅N₂S₂
• 分子量: 814.403
• InChiKey: KGKBCKGRFNRCQH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  23.3
• 重原子数：
  57
• 可旋转键数：
  36
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  60.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Heparanase inhibitors and uses thereof
  申请人：Van Gelder M. Joel

  公开号：US20070185176A1

  公开（公告）日：2007-08-09

  The invention provides heparanase inhibitors suitable for treatment of diseases and disorders caused by or associated with heparanase catalytic activity such as cancer, inflammatory disorders and autoimmune diseases.

  该发明提供了适用于治疗由或与肝素酶催化活性相关的疾病和疾病的肝素酶抑制剂，例如癌症，炎症性疾病和自身免疫疾病。
• Ion sensor
  申请人：MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.

  公开号：EP0570783A2

  公开（公告）日：1993-11-24

  Disclosed is an ion sensor whose electrode (1) is covered with a water-repelling organic chemically adsorbed film (2), which is formed with at least one hole (4) permitting the passage of ions but preventing the passage of biopolymers, (eg proteins in blood) thereby allowing accurate measurement of ion concentrations over a long period. In forming the silane-based chemically adsorbed monomolecular film (2) on the surface of the electrode, a hole dozens of angstroms in diameter is formed on an organic thin film by physically adsorbing the mask compound (3) and then washing it away. The sensor can also be used in a solution containing numerous impurities, and for monitoring ion activities in vivo by implanting it in the body.

  本发明公开了一种离子传感器，其电极（1）上覆盖有一层憎水的有机化学吸附薄膜（2），该薄膜上至少形成一个孔（4），允许离子通过，但阻止生物聚合物（如血液中的蛋白质）通过，从而可以长时间精确测量离子浓度。在电极表面形成硅烷基化学吸附单分子膜 (2) 时，通过物理吸附掩膜化合物 (3) 然后将其洗掉，在有机薄膜上形成一个直径为几十埃的孔。该传感器还可用于含有大量杂质的溶液中，以及通过植入人体来监测体内离子活动。
• Color-changing fishing equipment
  申请人：Cook B. Roger

  公开号：US20050274055A1

  公开（公告）日：2005-12-15

  Fishing equipment incorporates one or more dyes that change or display colors upon exposure to light (photochromic), a change in temperature (thermochromic), or change in ambient moisture (solvatochromic). Products that include parts that are made of, or products which are wholly a polymer can benefit from the present invention and may include fishing lines, fishing rods, fishing reels, thread used to wrap line guides on a fishing rod, and fishing reel handles.
• US5378344A
  申请人：——

  公开号：US5378344A

  公开（公告）日：1995-01-03