3,4,5-trihydroxy-N-[(3,4,5-trimethoxyphenyl)methylideneamino]benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 3,4,5-trihydroxy-N-[(3,4,5-trimethoxyphenyl)methylideneamino]benzamide
• 化学式: C₁₇H₁₈N₂O₇
• mdl: MFCD01335450
• 分子量: 362.3
• InChiKey: QJGCYJRRIYFNTP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  130
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA
  申请人：YALE UNIVERSITY

  公开号：US20210139512A1

  公开（公告）日：2021-05-13

  The present invention provides compositions and methods for inhibiting group II intron splicing for treating or preventing a disease or disorder associated with an organism harboring an active group II intron. The present invention also provides compositions and methods for inhibiting group II intron splicing for inhibiting, preventing or reducing growth of an organism harboring an active group II intron.