2-methyl-1,4-dihydro-4-(1'-naphthyl)-5-oxoindeno[1,2-b]pyridine-3-carbonitrile

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-methyl-1,4-dihydro-4-(1'-naphthyl)-5-oxoindeno[1,2-b]pyridine-3-carbonitrile
• 英文别名: 2-Methyl-4-naphthalen-1-yl-5-oxo-1,4-dihydroindeno[1,2-b]pyridine-3-carbonitrile
• 化学式: C₂₄H₁₆N₂O
• 分子量: 348.404
• InChiKey: BDKZGJJBDYQDRV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  27
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  52.9
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,3-茚满二酮 在 哌啶 作用下， 以 乙醇 、 溶剂黄146 为溶剂， 反应 4.0h， 生成 2-methyl-1,4-dihydro-4-(1'-naphthyl)-5-oxoindeno[1,2-b]pyridine-3-carbonitrile
  参考文献：
  名称：

  Synthesis and Reaction of Some Indenopyridine and Thieno[2,3-b]Indeno[2,1-e]Pyridine Derivatives

  摘要：

  Synthesis of indenopyridine-2-thione derivatives 6a-e via reaction of compound 1 with thioamides 2a-e in good yields. Several thieno[2,3-b]indeno[2,1-e]pyridine 9a-e have been synthesized. Some of them was used as a key intermediate in synthesis of 10-12. On the other hand, compound 1 reacted with various reagents to yield 16, 19, 21-24.

  DOI：

  10.1080/00397910008086945

文献信息

• Synthesis and Reaction of Some Indenopyridine and Thieno[2,3-b]Indeno[2,1-e]Pyridine Derivatives
  作者：Hassanein

  DOI：10.1080/00397910008086945

  日期：2000.11

  Synthesis of indenopyridine-2-thione derivatives 6a-e via reaction of compound 1 with thioamides 2a-e in good yields. Several thieno[2,3-b]indeno[2,1-e]pyridine 9a-e have been synthesized. Some of them was used as a key intermediate in synthesis of 10-12. On the other hand, compound 1 reacted with various reagents to yield 16, 19, 21-24.