2,13-Dimethyl-3,6,9,12,18-pentaazabicyclo(12.3.1)octadeca-1(18),14,16-triene | 54293-30-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2,13-Dimethyl-3,6,9,12,18-pentaazabicyclo(12.3.1)octadeca-1(18),14,16-triene
• 英文别名: 2,13-dimethyl-3,6,9,12,18-pentazabicyclo[12.3.1]octadeca-1(18),14,16-triene
• CAS: 54293-30-0
• 化学式: C₁₅H₂₇N₅
• 分子量: 277.41
• InChiKey: QMGACGSQPZVQLD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  61
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• METHODS AND COMPOUNDS FOR ENHANCING CONTRAST IN MAGNETIC RESONANCE IMAGING (MRI)
  申请人：Brock University

  公开号：US20160362434A1

  公开（公告）日：2016-12-15

  The present application relates to methods and compounds for enhancing contrast in magnetic resonance imaging. The methods comprise administering compounds of Formula I(a) or I(b) to a subject and obtaining a magnetic resonance image of the subject. The present application also relates to methods of preparing compounds of the Formula I(a) as well as intermediate compounds used in such a method of preparation.

  本申请涉及增强磁共振成像对比度的方法和化合物。该方法包括向受试者注射I(a)或I(b)公式的化合物，并获取受试者的磁共振图像。本申请还涉及制备I(a)公式化合物的方法，以及用于此类制备方法的中间化合物。
• Methods and compounds for enhancing contrast in magnetic resonance imaging (MRI)
  申请人：Brock University

  公开号：US10377783B2

  公开（公告）日：2019-08-13

  The present application relates to methods and compounds for enhancing contrast in magnetic resonance imaging. The methods comprise administering compounds of Formula I(a) or I(b) to a subject and obtaining a magnetic resonance image of the subject. The present application also relates to methods of preparing compounds of the Formula I(a) as well as intermediate compounds used in such a method of preparation.

  本申请涉及增强磁共振成像对比度的方法和化合物。这些方法包括向受试者施用式 I(a)或 I(b)化合物并获得受试者的磁共振图像。本申请还涉及制备式 I(a)化合物的方法以及用于这种制备方法的中间化合物。