1-[1-(4-Phenylmethoxyphenyl)ethyl]naphthalen-2-ol | 1166901-37-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-[1-(4-Phenylmethoxyphenyl)ethyl]naphthalen-2-ol
• CAS: 1166901-37-6
• 化学式: C₂₅H₂₂O₂
• 分子量: 354.448
• InChiKey: IAUWTGZXEPYCDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-(4-(benzyloxy)phenyl)ethanol 、 2-萘酚 在 amberlyst-15 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 1.0h， 以82%的产率得到1-[1-(4-Phenylmethoxyphenyl)ethyl]naphthalen-2-ol
  参考文献：
  名称：

  Benzylation and Allylation of Naphthols Using Amberlyst-15

  摘要：

  A simple and efficient method has been developed for benzylation and allylation of naphthols by treatment of the compounds with benzylic and allylic alcohols, respectively, in the presence of amberlyst-15. Several heterogeneous catalysts were screened for the reaction, and amberlyst-15 was found to be most effective.

  DOI：

  10.1080/00397910802621715

文献信息

• Benzylation and Allylation of Naphthols Using Amberlyst-15
  作者：Biswanath Das、Boyapati Veeranjaneyulu、Maddeboina Krishnaiah、P. Balasubramanyam

  DOI：10.1080/00397910802621715

  日期：2009.5.7

  A simple and efficient method has been developed for benzylation and allylation of naphthols by treatment of the compounds with benzylic and allylic alcohols, respectively, in the presence of amberlyst-15. Several heterogeneous catalysts were screened for the reaction, and amberlyst-15 was found to be most effective.