N-(1-benzothiophen-3-ylmethyl)methanesulfonamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: N-(1-benzothiophen-3-ylmethyl)methanesulfonamide
• 化学式: C₁₀H₁₁NO₂S₂
• 分子量: 241.3
• InChiKey: ABRJHAOVFSCTPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  82.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• CRYSTALLINE FORMS OF N-(BENZO[B]THIEN-3-YLMETHYL)-SULFAMIDE
  申请人：Fawzy Nagy

  公开号：US20070232685A1

  公开（公告）日：2007-10-04

  The present invention is directed to anhydrous and solvated, crystalline forms of N-(benzo[b]thien-3-ylmethyl)-sulfamide, pharmaceutical compositions containing said crystalline forms and their use in the treatment epilepsy and related disorders.

  本发明涉及N-(苯并[b]噻吩-3-基甲基)-磺酰胺的无水和溶剂化结晶形式，含有该晶体形式的制药组合物及其在治疗癫痫和相关疾病中的应用。
• SULFAMIDE DERIVATIVE USEFUL FOR THE TREATMENT OF EPILEPSY
  申请人：Breslav Michael

  公开号：US20090176865A1

  公开（公告）日：2009-07-09

  The present invention is directed to novel sulfamide derivatives, pharmaceutical compositions comprising said compounds and methods for the treatment of epilepsy and related disorders comprising administering to a subject in need thereof, said compounds, either alone or as co-therapy with one or more anticonvulsant and/or anti-epileptic agents.
• US7897636B2
  申请人：——

  公开号：US7897636B2

  公开（公告）日：2011-03-01