Methyl(cyclopentyl-propyl)amine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Methyl(cyclopentyl-propyl)amine
• 英文别名: 3-cyclopentyl-N-methylpropan-1-amine
• 化学式: C₉H₁₉N
• 分子量: 141.25
• InChiKey: XQXPWKNEZKBRNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Diaminoalkane Aspartic Protease Inhibitors
  申请人：Baldwin John J.

  公开号：US20090018103A1

  公开（公告）日：2009-01-15

  Diaminoalkanes of Formula I have now been found which are orally active and bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with elevated levels of aspartic protease activity. The invention also relates to a method for the use of the compounds of Formula I in ameliorating or treating aspartic protease related disorders in a subject in need thereof comprising administering to said subject an effective amount of a compound of Formula I.

  公式I的Diaminoalkanes现已被发现，它们具有口服活性并结合到天冬氨酸蛋白酶以抑制其活性。它们在治疗或改善与天冬氨酸蛋白酶活性升高相关的疾病方面非常有用。本发明还涉及使用公式I化合物治疗或改善需要的天冬氨酸蛋白酶相关疾病的方法，包括向该受体施用公式I化合物的有效量。
• Diaminoalkane aspartic protease inhibitors
  申请人：Baldwin John J.

  公开号：US20110105506A1

  公开（公告）日：2011-05-05

  Diaminoalkanes of Formula I have now been found which are orally active and bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with elevated levels of aspartic protease activity. The invention also relates to a method for the use of the compounds of Formula I in ameliorating or treating aspartic protease related disorders in a subject in need thereof comprising administering to said subject an effective amount of a compound of Formula I.

  公式I的二氨基烷已被发现具有口服活性并能结合天冬氨酸蛋白酶以抑制其活性。它们可用于治疗或改善与天冬氨酸蛋白酶活性升高相关的疾病。本发明还涉及一种使用公式I化合物改善或治疗需要的天冬氨酸蛋白酶相关疾病的方法，包括向该受试者施用有效量的公式I化合物。
• AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS
  申请人：ZERIA PHARMACEUTICAL CO., LTD.

  公开号：EP0870765A1

  公开（公告）日：1998-10-14

  The present invention relates to an aminothiazole derivative represented by the following formula (I): wherein R1, R2 and R3 each independently represents a hydrogen atom, a hydroxy group, a lower alkyl group, a lower alkoxy group or the like; R4 represents a hydrogen atom or a lower alkyl group; R5 represents a hydrogen atom, a halogen atom or a lower alkyl group; m stands for an integer of 0 to 4, A represents a substituted amino group, a substituted imino group, a heterocyclic group or the like; and B stands for an imino group or an oxygen atom, a medicament containing it and an intermediate for the preparation of said compound. The compound has strong restoration effects on dysmotility in the gastrointestinal tract and at the same time has high safety so that it is useful as an excellent gastroprokinetic.

  本发明涉及下式（I）所代表的氨基噻唑衍生物： 其中 R1、R2 和 R3 各自独立地代表氢原子、羟基、低级烷基、低级烷氧基或类似基团；R4 代表氢原子或低级烷基；R5 代表氢原子、卤素原子或低级烷基；m 代表 0 至 4 的整数；A 代表取代的氨基、取代的亚氨基、杂环基团或类似基团；B 代表亚氨基或氧原子。该化合物对胃肠道运动障碍有很强的修复作用，同时具有很高的安全性，因此可作为一种很好的胃动力药。
• System, apparatus and method for providing an interactive inspection map
  申请人：Gecko Robotics, Inc.

  公开号：US11518030B2

  公开（公告）日：2022-12-06

  Systems, apparatus and methods for providing an interactive inspection map are disclosed. An example apparatus for providing an interactive inspection map of an inspection surface may include an inspection visualization circuit to provide an inspection map to a user device in response to inspection data provided by a plurality of sensors operationally coupled to an inspection robot traversing the inspection surface, wherein the inspection map corresponds to at least a portion of the inspection surface. The apparatus may further include a user interaction circuit to interpret a user focus value from the user device, and an action request circuit to determine an action in response to the user focus value. The inspection visualization circuit may further update the inspection map in response to the determined action.

  本文公开了用于提供交互式检测地图的系统、装置和方法。提供检测表面的交互式检测地图的示例装置可包括检测可视化电路，用于响应由多个传感器提供的检测数据，向用户设备提供检测地图，这些传感器在操作上耦合到穿越检测表面的检测机器人，其中检测地图对应于检测表面的至少一部分。设备可进一步包括用户交互电路，用于解释来自用户设备的用户关注值；以及操作请求电路，用于确定响应于用户关注值的操作。检测可视化电路可进一步更新检测地图，以响应确定的操作。
• US5541229A
  申请人：——

  公开号：US5541229A

  公开（公告）日：1996-07-30