(2R)-hexane-1,2-diamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (2R)-hexane-1,2-diamine
• 化学式: C₆H₁₆N₂
• 分子量: 116.2
• InChiKey: JVQUBHIPPUVHCN-ZCFIWIBFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Bacterial efflux pump inhibitors
  申请人：RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

  公开号：US10836706B2

  公开（公告）日：2020-11-17

  Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.

  本文公开了式 I 化合物及其盐类。还公开了包含式 I 化合物的组合物以及使用式 I 化合物的方法。
• TOLL-LIKE RECEPTOR MODULATING 4,6-DIAMINO-PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS
  申请人：Gilead Sciences, Inc.

  公开号：EP3097102B1

  公开（公告）日：2017-10-18
• TOLL LIKE RECEPTOR MODULATOR COMPOUNDS
  申请人：Gilead Sciences, Inc.

  公开号：US20170281627A1

  公开（公告）日：2017-10-05

  The present disclosure relates generally to toll like receptor modulator compounds, such as diamino pyrido[3,2 D] pyrimidine compounds and pharmaceutical compositions which, among other things, modulate toll-like receptors (e.g. TLR-8), and methods of making and using them.
• BACTERIAL EFFLUX PUMP INHIBITORS
  申请人：RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

  公开号：US20190055188A1

  公开（公告）日：2019-02-21

  Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
• [EN] FUSED TRICYCLIC HETEROCYCLIC COMPOUNDS USEFUL FOR TREATING HIV INFECTION<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES TRICYCLIQUES CONDENSÉS UTILES POUR TRAITER UNE INFECTION PROVOQUÉE PAR LE VIH
  申请人：MERCK SHARP & DOHME

  公开号：WO2016191239A1

  公开（公告）日：2016-12-01

  The present invention relates to Fused Tricyclic Heterocycle Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, m, R1, R2, R3, R3, R3, R4, R5 and R9 are as defined herein. The present invention also relates to compositions comprising at least one Fused Tricyclic Heterocycle Derivative, and methods of using the Fused Tricyclic Heterocycle Derivatives for treating or preventing HIV infection in a subject.