(1-Butylimidazol-2-yl)methanamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (1-Butylimidazol-2-yl)methanamine
• 化学式: C₈H₁₅N₃
• mdl: MFCD08704459
• 分子量: 153.22
• InChiKey: LXKDNTVSXMDYTF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  43.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PLATINUM (IV) COMPLEXES
  申请人：Platco Technologies (Proprietary) Limited

  公开号：EP2170913A1

  公开（公告）日：2010-04-07
• Platinum (IV) Complexes
  申请人：Du Preez Jan Gysbert Hermanus

  公开号：US20110021483A1

  公开（公告）日：2011-01-27

  Provided are nitroplatinum(IV) complexes containing a bidentate dicarboxylate ligand (e.g., oxalate) which maybe useful treating various forms of proliferative diseases, such as cancer. In some instances the platinum(IV) complexes are relatively stable and may be suitable for oral administration. Also provided are methods of treatment, as well as kits and unit dosages.
• [EN] PLATINUM (IV) COMPLEXES<br/>[FR] COMPLEXES DE PLATINE (IV)
  申请人：PLATCO TECHNOLOGIES PROPRIETAR

  公开号：WO2008155727A1

  公开（公告）日：2008-12-24

  [EN] Provided are nitroplatinum(IV) complexes containing a bidentate dicarboxylate ligand (e.g., oxalate) which maybe useful treating various forms of proliferative diseases, such as cancer. In some instances the platinum(IV) complexes are relatively stable and may be suitable for oral administration. Also provided are methods of treatment, as well as kits and unit dosages.
  [FR] L'invention porte sur des complexes de nitro-platine (IV) contenant un ligand de dicarboxylate bidentate (par exemple un oxalate) qui peut être utile pour traiter diverses formes de maladies prolifératives, telles que le cancer. Dans certains cas, les complexes de platine (IV) sont relativement stables et peuvent être appropriés pour une administration orale. L'invention concerne également des procédés de traitement, ainsi que des coffrets et des unités de dosage.