19-Chlor-testosteron | 5884-92-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 19-Chlor-testosteron
• 英文别名: 19-Chloro-17beta-hydroxyandrost-4-en-3-one；(8S,9S,10S,13S,14S,17S)-10-(chloromethyl)-17-hydroxy-13-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
• CAS: 5884-92-4
• 化学式: C₁₉H₂₇ClO₂
• 分子量: 322.875
• InChiKey: FHHUNXIPEAHYQC-KOUJMVCDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• BIOMARKERS FOR MALARIA DIAGNOSIS
  申请人：The United States of America, as represented by the Secretary, Dept. of Health and Human Services

  公开号：US20180052161A1

  公开（公告）日：2018-02-22

  Disclosed herein are methods of detecting Plasmodium in a subject (for example, presence of Plasmodium parasite) by detecting the presence and/or amount of one or more metabolites in a sample from the subject. In some embodiments, the methods include detecting in the sample one or more metabolites listed in Table 1, Table 2, and/or Tables 5-8. The amount of the one or more metabolites in the sample is compared to the amount of the one or more metabolites in a control and presence of Plasmodium is determined if the amount of the one or more metabolites is different (for example statistically significantly increased or decreased) compared to the control.
• [EN] BIOMARKERS FOR MALARIA DIAGNOSIS<br/>[FR] BIOMARQUEURS POUR LE DIAGNOSTIC DU PALUDISME
  申请人：THE US SECRETARY DEPT OF HEALTH & HUMAN SERVICES

  公开号：WO2016149386A1

  公开（公告）日：2016-09-22

  Disclosed herein are methods of detecting Plasmodium in a subject (for example, presence of Plasmodium parasite) by detecting the presence and/or amount of one or more metabolites in a sample from the subject. In some embodiments, the methods include detecting in the sample one or more metabolites listed in Table 1, Table 2, and/or Tables 5-8. The amount of the one or more metabolites in the sample is compared to the amount of the one or more metabolites in a control and presence of Plasmodium is determined if the amount of the one or more metabolites is different (for example statistically significantly increased or decreased) compared to the control.