3-[(Z)-2-(3-hydroxyphenyl)ethenyl]phenol | 135781-00-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 3-[(Z)-2-(3-hydroxyphenyl)ethenyl]phenol
• CAS: 135781-00-9
• 化学式: C₁₄H₁₂O₂
• 分子量: 212.248
• InChiKey: VLOHFQFIKQIMBT-FPLPWBNLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-羟基苯甲酸甲酯 在 lithium aluminium tetrahydride 、 titanium(III) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 23.0h， 以44%的产率得到3-[(Z)-2-(3-hydroxyphenyl)ethenyl]phenol
  参考文献：
  名称：

  Dang, Y.; Geise, H. J., Bulletin des Societes Chimiques Belges, 1991, vol. 100, # 5, p. 375 - 380

  摘要：

  DOI：

文献信息

• KINASE INHIBITOR COMPOUNDS
  申请人：Sayeski Peter P.

  公开号：US20110301159A1

  公开（公告）日：2011-12-08

  The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof.
• VIMENTIN AS A BIOMARKER FOR THE PROGRESSION OF MYELOPROLIFERATIVE NEOPLASMS
  申请人：University of Florida Research Foundation

  公开号：US20140248634A1

  公开（公告）日：2014-09-04

  The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof.
• [EN] KINASE INHIBITOR COMPOUNDS<br/>[FR] COMPOSÉS INHIBITEURS DE KINASE
  申请人：UNIV FLORIDA

  公开号：WO2010068710A2

  公开（公告）日：2010-06-17

  The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof.
• [EN] VIMENTIN AS A BIOMARKER FOR THE PROGRESSION OF MYELOPROLIFERATIVE NEOPLASMS<br/>[FR] UTILISATION DE LA VIMENTINE COMME BIOMARQUEUR DE L'ÉVOLUTION DES NÉOPLASMES MYÉLOPROLIFÉRATIFS
  申请人：UNIV FLORIDA

  公开号：WO2013019655A2

  公开（公告）日：2013-02-07

  The disclosure relates to novel compounds that are capable of modulating Jak2 kinase activities, compounds that have therapeutic use in treating or preventing a subject suffering from or susceptible to a Jak2 mediated disease or disorder, and methods of use and compositions thereof.
• Dang, Y.; Geise, H. J., Bulletin des Societes Chimiques Belges, 1991, vol. 100, # 5, p. 375 - 380
  作者：Dang, Y.、Geise, H. J.

  DOI：——

  日期：——