5--3-methyl-uracil | 62785-09-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 5--3-methyl-uracil
• 英文别名: 5-[bis-(2-chloro-ethyl)-amino]-3-methyl-1H-pyrimidine-2,4-dione；Uracil, 5-[bis(2-chloroethyl)amino]-3-methyl-；5-[bis(2-chloroethyl)amino]-3-methyl-1H-pyrimidine-2,4-dione
• CAS: 62785-09-5
• 化学式: C₉H₁₃Cl₂N₃O₂
• 分子量: 266.127
• InChiKey: QVQYGGLXCDUVOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  52.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• BIOORTHOGONAL METHODS AND COMPOUNDS
  申请人：THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH

  公开号：US20160152573A1

  公开（公告）日：2016-06-02

  The invention provides a new bioorthogonal deprotection method for preparing heterocyclic compounds by bond cleavage using palladium. The methods have general application in the field of biological synthetic chemistry. Compounds, such as prodrugs, which are useful in such methods are also provided.