6-Methoxy-7-methyl-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalin | 22825-12-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 6-Methoxy-7-methyl-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalin
• 英文别名: 6-Methoxy-1,1,4,4,7-pentamethyl-2,3-dihydronaphthalene
• CAS: 22825-12-3
• 化学式: C₁₆H₂₄O
• 分子量: 232.366
• InChiKey: XVHMNFOYSORWCS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• REDOX SHUTTLES HAVING AN AROMATIC RING FUSED TO A 1,1,4,4-TETRASUBSTITUTED CYCLOHEXANE RING
  申请人：Weng Wei

  公开号：US20130288137A1

  公开（公告）日：2013-10-31

  An electrolyte includes an alkali metal salt; an aprotic solvent; and a redox shuttle additive including an aromatic compound having at least one aromatic ring fused with at least one non-aromatic ring, the aromatic ring having two or more oxygen or phosphorus-containing substituents.

  一个电解质包括碱金属盐；无质子溶剂；和一个氧化还原穿梭添加剂，其中包括一个芳香化合物，该芳香环至少与一个非芳香环融合，芳香环具有两个或更多含氧或含磷的取代基。
• Tricyclic hydroxamate and benzamide derivatives, compositions and methods
  申请人：Leblond Bertrand

  公开号：US20070129368A1

  公开（公告）日：2007-06-07

  The present invention relates to compounds and methods for inhibiting histone deacetylase enzymatic activity. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit histone deacetylases (IIDACs), and in the treatment of conditions mediated by HDAC, cancer, proliferative conditions, psoriasis, and also central nervous system diseases. It further deals with processes for preparing said compounds.

  本发明涉及化合物和方法，用于抑制组蛋白去乙酰化酶的酶活性。本发明还涉及包含这种化合物的制药组合物，以及在体外和体内使用这种化合物和组合物来抑制组蛋白去乙酰化酶（IIDACs）并用于治疗由HDAC介导的疾病，如癌症，增殖性疾病，牛皮癣以及中枢神经系统疾病。此外，本发明还涉及制备所述化合物的过程。
• TRICYCLIC HYDROXAMATE AND BENZAMIDE DERIVATIVES, COMPOSITIONS AND METHODS
  申请人：Exonhit Therapeutics SA

  公开号：EP1692097B1

  公开（公告）日：2009-09-02
• US7923579B2
  申请人：——

  公开号：US7923579B2

  公开（公告）日：2011-04-12
• US9203112B2
  申请人：——

  公开号：US9203112B2

  公开（公告）日：2015-12-01