N2,N5,2,5-Tetramethylhexane-2,5-diamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N2,N5,2,5-Tetramethylhexane-2,5-diamine
• 英文别名: 2-N,5-N,2,5-tetramethylhexane-2,5-diamine
• 化学式: C₁₀H₂₄N₂
• 分子量: 172.31
• InChiKey: QWNANNUFHAXXTP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• PRMT1 INHIBITORS AND USES THEREOF
  申请人：Epizyme, Inc.

  公开号：US20140288140A1

  公开（公告）日：2014-09-25

  Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.

  本文描述了式（I）的化合物，其药用盐以及药物组成物。本文描述的化合物可用于抑制PRMT1活性。还描述了使用这些化合物治疗PRMT1介导的疾病的方法。
• POLYURETHANE/POLYUREA SPRAY ELASTOMERS
  申请人：Dow Global Technologies LLC

  公开号：EP2552990B1

  公开（公告）日：2017-04-19
• [EN] PHOSPHORUS-CONTAINING SECONDARY AMINE COMPOUNDS<br/>[FR] COMPOSÉS AMINES SECONDAIRES À TENEUR EN PHOSPHORE
  申请人：HUNTSMAN PETROCHEMICAL LLC

  公开号：WO2013009372A1

  公开（公告）日：2013-01-17

  Phosphate-containing secondary amine compounds are used in polymers, polyurethanes, coating compositions and epoxy compositions. A phosphorus-containing secondary amine compound comprising the reaction product of a polyamine compound, a carbonyl compound, and a phosphorus-containing compound. A phosphorus-containing primary amine may be formed by reducing the phosphorus-containing secondary amine compound and an acrylonitrile. A polymer is provided comprising the reaction product of an isocyanate compound, the phosphorus-containing secondary amine compound, and, optionally, a polyol compound and one or more additives, wherein the polymer comprises a urea moiety, a urethane moiety, or combinations thereof.