5-Hydroxyconiferaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-Hydroxyconiferaldehyde
• 英文别名: (E)-3-(3,4-dihydroxy-5-methoxyphenyl)prop-2-enal
• 化学式: C₁₀H₁₀O₄
• 分子量: 194.18
• InChiKey: IEHPLRVWOHZKCS-NSCUHMNNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Altering regulation of maize lignin biosynthesis enzymes via RNAi technology
  申请人：Sticklen Masomeh B.

  公开号：US20080213871A1

  公开（公告）日：2008-09-04

  The present invention relates to compositions and methods for providing RNA Interference (RNAi) vectors comprising maize lignin biosynthesis enzymes for altering lignin content of plants. Specifically, plants comprising RNAi maize lignin vectors for reducing or altering lignin content are provided for reducing pretreatment costs of biofuel production. Additionally, RNAi maize lignin vectors are provided for altering cellulose production in plants for reducing pretreatment costs of plant biomass processing by increasing amounts of fermentable sugars.

  本发明涉及用于提供RNA干扰（RNAi）载体的组合物和方法，其中包括玉米木质素生物合成酶，以改变植物的木质素含量。具体而言，提供了包含RNAi玉米木质素载体的植物，以减少或改变木质素含量，以降低生物燃料生产的预处理成本。此外，提供了RNAi玉米木质素载体，以改变植物的纤维素产量，通过增加可发酵糖的量来降低植物生物质加工的预处理成本。
• Probe compound for detecting and isolating enzymes and means and methods using the same
  申请人：Helmholtz-Zentrum für Infektionsforschung GmbH

  公开号：EP2230312A1

  公开（公告）日：2010-09-22

  The present invention relates to a probe compound that can comprise any substrate or metabolite of an enzymatic reaction in addition to an indicator component, such as, for example, a fluorescence dye, or the like. Moreover, the present invention relates to means for detecting enzymes in form of an array, which comprises any number of probe compounds of the invention which each comprise a different metabolite of interconnected metabolites representing the central pathways in all forms of life. Moreover, the present invention relates to a method for detecting enzymes involving the application of cell extracts or the like to the array of the invention which leads to reproducible enzymatic reactions with the substrates. These specific enzymatic reactions trigger the indicator (e.g. a fluorescence signal) and bind the enzymes to the respective cognate substrates. Moreover, the invention relates to means for isolating enzymes in form of nanoparticles coated with the probe compound of the invention. The immobilisation of the cognate substrates or metabolites on the surface of nanoparticles by means of the probe compounds allows capturing and isolating the respective enzyme, e.g. for subsequent sequencing.

  本发明涉及一种探针化合物，它可以包括酶反应的任何底物或代谢物，此外还包括指示成分，例如荧光染料或类似物。此外，本发明还涉及以阵列形式检测酶的方法，该阵列由任意数量的本发明探针化合物组成，每种探针化合物由代表所有生命形式中中心途径的相互关联的代谢物中的不同代谢物组成。此外，本发明还涉及一种检测酶的方法，该方法涉及将细胞提取物或类似物应用于本发明的阵列，从而导致与底物发生可重复的酶反应。这些特定的酶反应会触发指示剂（如荧光信号），并将酶与各自的同源底物结合。此外，本发明还涉及以涂覆有本发明探针化合物的纳米颗粒形式分离酶的方法。通过探针化合物将同源底物或代谢物固定在纳米颗粒表面，可以捕获和分离相应的酶，例如用于后续测序。
• Modification of plant lignin content
  申请人：ArborGen Inc.

  公开号：EP2520657A2

  公开（公告）日：2012-11-07

  DNA constructs comprising a first DNA segment that corresponds to at least a portion of a gene in the monolignol biosynthetic pathway, a spacer DNA segment, and a second DNA segment that is complementary to the first DNA segment can be used to reduce or modulate the lignin content in plants. In some embodiments, DNA constructs comprise at least a portion of a gene for 4CL, C3H, CCR, C4H, CaId5H, SAD or CCoAOMT. Vascular-preferred and constitutive promoters can be used to drive expression of the constructs.

  DNA 构建体包括与单木质素生物合成途径中的至少部分基因相对应的第一 DNA 片段、间隔 DNA 片段和与第一 DNA 片段互补的第二 DNA 片段，可用于减少或调节植物中的木质素含量。在某些实施方案中，DNA 构建体至少包括 4CL、C3H、CCR、C4H、CaId5H、SAD 或 CCoAOMT 基因的一部分。血管偏好型启动子和组成型启动子可用于驱动构建体的表达。
• Means and methods for altering the lignin pathway in plants
  申请人：VIB VZW

  公开号：US10006041B2

  公开（公告）日：2018-06-26

  The disclosure generally relates to the field of molecular biology, specifically the field of agricultural biology. In particular, the disclosure relates to means and methods for modifying the lignin flu and composition in plants. In particular, the disclosure provides chimeric genes comprising transaldolase sequences, which can be used in the context of this disclosure.

  本公开一般涉及分子生物学领域，特别是农业生物学领域。特别是，本公开涉及改变植物中木质素流体和组成的手段和方法。特别是，本公开提供了包含转醛酸酶序列的嵌合基因，可用于本公开的上下文中。
• Methods and compositions for enhanced forage quality
  申请人：Monsanto Technology LLC

  公开号：US10704053B2

  公开（公告）日：2020-07-07

  The invention provides a method to select an alfalfa plant with enhanced feed value and increased flexibility in management either to increase quality of forage provided or to enhance biomass available earlier.

  本发明提供了一种选择苜蓿植物的方法，这种苜蓿植物具有更高的饲料价值和更大的管理灵活性，可以提高所提供饲料的质量，或更早地提高可利用的生物量。