Arginyl-benzothiazole-6-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: Arginyl-benzothiazole-6-carboxylic acid
• 英文别名: 2-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]-1,3-benzothiazole-6-carboxylic acid
• 化学式: C₁₄H₁₇N₅O₃S
• 分子量: 335.38
• InChiKey: FNGTVLJWXRDWAE-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  186
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• Compositions of multimeric-multiepitope influenza polypeptides and their production
  申请人：BiondVax Pharmaceuticals Ltd.

  公开号：US10426828B2

  公开（公告）日：2019-10-01

  Pharmaceutical suspensions of multimeric-multiepitope influenza polypeptides, processes for their production and their use as immunizing subjects against influenza. In particular, stable aqueous microparticulate suspensions of a multimeric multiepitope polypeptide are disclosed.

  多聚多肽流感多肽的药用悬浮液、其生产工艺及其作为流感免疫对象的用途。特别是公开了多聚多肽的稳定水性微颗粒悬浮液。
• COMPOSITIONS OF MULTIMERIC-MULTIEPITOPE INFLUENZA POLYPEPTIDES AND THEIR PRODUCTION
  申请人：Biondvax Pharmaceuticals Ltd.

  公开号：EP3125931A1

  公开（公告）日：2017-02-08
• [EN] COMPOSITIONS OF MULTIMERIC-MULTIEPITOPE INFLUENZA POLYPEPTIDES AND THEIR PRODUCTION<br/>[FR] COMPOSITIONS DE POLYPEPTIDES MULTIMÈRES-MULTI-ÉPITOPES DE GRIPPE ET LEUR PRODUCTION
  申请人：BIONDVAX PHARMACEUTICALS LTD

  公开号：WO2015151103A1

  公开（公告）日：2015-10-08

  The present invention relates to pharmaceutical suspensions comprising multimeric- multiepitope influenza polypeptides, to processes for their production and to their use as immunizing subjects against influenza. In particular, the invention relates to stable aqueous microparticulate suspensions comprising a multimeric multiepitope polypeptide.