leucovorin | 54353-24-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: leucovorin
• 英文别名: folinic acid；Pteroyl-D-glutamic acid；(2R)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
• CAS: 54353-24-1
• 化学式: C₂₀H₂₃N₇O₇
• 分子量: 473.445
• InChiKey: VVIAGPKUTFNRDU-ZGTCLIOFSA-N

物化性质

• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  34
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  216
• 氢给体数：
  7
• 氢受体数：
  10

文献信息

• COMPOSITION OF MULTIVITAMIN FOR STIMULATING GASTROINTESTINAL SYSTEM MOTILITY AND PREPARATION METHOD THEREFOR
  申请人：Zensun (Shanghai) Science and Technology, Co., Ltd.

  公开号：EP3811947A1

  公开（公告）日：2021-04-28

  The present invention relates to a composition of a multivitamin, vitamins B and C, and a preparation method therefor, and in particular, to a composition of a multivitamin, vitamins B and C for stimulating gastrointestinal system motility and a preparation method therefor. The composition is suitable for preventing and/or treating the statuses or diseases related to a lack of gastrointestinal motility.

  本发明涉及一种由多种维生素、维生素 B 和维生素 C 组成的组合物及其制备方法，特别是涉及一种用于刺激胃肠道系统蠕动的由多种维生素、维生素 B 和维生素 C 组成的组合物及其制备方法。该组合物适用于预防和/或治疗与胃肠动力不足有关的状态或疾病。
• Foliar fertilizer compositions and methods for using same
  申请人：Yamashita Thomas T.

  公开号：US11286212B2

  公开（公告）日：2022-03-29

  Aspects of the present disclosure include foliar fertilizer compositions. Compositions according to certain embodiments include a source of a plant growth regulator, an ionophore and water. Methods for applying the compositions to the foliage of plants to enhance plant growth (e.g., enhance heat tolerance and cold stress, increase photosynthetic activity) and kits having one or more fertilizer composition for applying to the foliage of a plant are also described.

  本发明公开的某些方面涉及叶面肥料组合物。根据某些实施例的组合物包括植物生长调节剂的来源、离子载体和水。将所述组合物施加到植物叶面上以促进植物生长的方法（例如增强耐热性和抗寒性、提高光合作用活性）以及包含一种或多种用于施加到植物叶面的肥料组合物的试剂盒也进行了描述。
• USE OF VITAMIN COMPOSITION IN PREPARING DRUG FOR PREVENTING, TREATING, OR DELAYING ALZHEIMER'S DISEASE
  申请人：Zensun (Shanghai) Science & Technology, Co., Ltd.

  公开号：US20200030358A1

  公开（公告）日：2020-01-30

  A use of a vitamin composition in preparing a drug for preventing, treating, or delaying Alzheimer's disease. The composition comprises a B vitamins composition or an analog or derivative thereof, vitamin C or an analog or derivative thereof, or a combination of a B vitamins composition or an analog or derivative thereof with vitamin C or an analog or derivative thereof.
• Foliar Fertilizer Compositions and Methods for Using Same
  申请人：Yamashita Thomas T.

  公开号：US20200048156A1

  公开（公告）日：2020-02-13

  Aspects of the present disclosure include foliar fertilizer compositions. Compositions according to certain embodiments include a source of a plant growth regulator, an ionophore and water. Methods for applying the compositions to the foliage of plants to enhance plant growth (e.g., enhance heat tolerance and cold stress, increase photosynthetic activity) and kits having one or more fertilizer composition for applying to the foliage of a plant are also described.
• [EN] COMPOSITION COMPRISING METHYLFOLATE<br/>[FR] COMPOSITION COMPRENANT DU MÉTHYLFOLATE
  申请人：ALFASIGMA SPA

  公开号：WO2021228788A1

  公开（公告）日：2021-11-18

  The present invention describes a pharmaceutical and/or nutritional composition comprising methylfolate in the form of granules, together with a carnitine derivative salt, pharmaceutically acceptable excipients, and optionally other pharmaceutical or nutraceutical active ingredients. The composition is useful for oral administration. The invention also relates to the process for obtaining the composition comprising methylfolate in the form of granules and the use thereof for the treatment of disorders associated with a reduction of methylfolate, wherein methylfolate is useful.