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    —— [7-[chloro(difluoro)methyl]-5-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2R)-6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl]methanone —— C22H16ClF3N4O2
    [7-[chloro(difluoro)methyl]-5-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2R)-6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl]methanone
    —— [7-[chloro(difluoro)methyl]-5-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2S)-6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl]methanone —— C22H16ClF3N4O2
    [7-[chloro(difluoro)methyl]-5-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2S)-6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl]methanone
    —— 7-(4-chlorophenyl)-1,3-dimethyl-8-phenyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione —— C21H16ClN5O2
    7-(4-chlorophenyl)-1,3-dimethyl-8-phenyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
    —— 7-(Chlorodifluoromethyl)-N-cyclopropyl-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C15H11ClF2N4OS
    7-(Chlorodifluoromethyl)-N-cyclopropyl-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-(5-fluoro-2-methylphenyl)-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C19H12ClF3N4OS
    7-(Chlorodifluoromethyl)-N-(5-fluoro-2-methylphenyl)-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-[2-(2-chlorophenyl)ethyl]-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C20H14Cl2F2N4OS
    7-(Chlorodifluoromethyl)-N-[2-(2-chlorophenyl)ethyl]-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-Ethyl-3-(4-fluorobenzoyl)-1,2-bis(propane-1-sulfonyl)indolizine —— C23H26FNO5S2
    7-Ethyl-3-(4-fluorobenzoyl)-1,2-bis(propane-1-sulfonyl)indolizine
    —— 7-[chloro(difluoro)methyl]-N-(3-pyridinylmethyl)-5-(2-thienyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C18H12ClF2N5OS
    7-[chloro(difluoro)methyl]-N-(3-pyridinylmethyl)-5-(2-thienyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— 7-(difluoromethyl)-N-methyl-5-phenyl-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H15F5N4O2
    7-(difluoromethyl)-N-methyl-5-phenyl-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-[(4-fluorophenyl)methyl]-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C19H12ClF3N4OS
    7-(Chlorodifluoromethyl)-N-[(4-fluorophenyl)methyl]-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-5-(thiophen-2-YL)-N-[2-(trifluoromethyl)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C19H10ClF5N4OS
    7-(Chlorodifluoromethyl)-5-(thiophen-2-YL)-N-[2-(trifluoromethyl)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-[chloro(difluoro)methyl]-N-[[(2R)-oxolan-2-yl]methyl]-5-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-2-carboxamide —— C17H15ClF2N4O2S
    7-[chloro(difluoro)methyl]-N-[[(2R)-oxolan-2-yl]methyl]-5-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-cyclooctyl-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C20H21ClF2N4OS
    7-(Chlorodifluoromethyl)-N-cyclooctyl-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-methyl-5-(thiophen-2-YL)-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C20H12ClF5N4O2S
    7-(Chlorodifluoromethyl)-N-methyl-5-(thiophen-2-YL)-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(3-Methoxyphenyl)-8-(4-methoxyphenyl)-1,3-dimethyl-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione —— C23H21N5O4
    7-(3-Methoxyphenyl)-8-(4-methoxyphenyl)-1,3-dimethyl-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione
    —— 7-(Chlorodifluoromethyl)-5-(thiophen-2-YL)-N-[(thiophen-2-YL)methyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C17H11ClF2N4OS2
    7-(Chlorodifluoromethyl)-5-(thiophen-2-YL)-N-[(thiophen-2-YL)methyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-[2-(1H-indol-3-YL)ethyl]-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C22H16ClF2N5OS
    7-(Chlorodifluoromethyl)-N-[2-(1H-indol-3-YL)ethyl]-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(4-Chlorophenyl)-1,3-dimethyl-8-(2-phenylethyl)-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione —— C23H20ClN5O2
    7-(4-Chlorophenyl)-1,3-dimethyl-8-(2-phenylethyl)-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione
    —— 7-(Chlorodifluoromethyl)-5-(thiophen-2-YL)-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C19H10ClF5N4O2S
    7-(Chlorodifluoromethyl)-5-(thiophen-2-YL)-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(4-fluorophenyl)-1,3-dimethyl-8-[3-(trifluoromethyl)phenyl]-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione —— C22H15F4N5O2
    7-(4-fluorophenyl)-1,3-dimethyl-8-[3-(trifluoromethyl)phenyl]-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
    —— 7-[chloro(difluoro)methyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-2-carboxamide —— C17H15ClF2N4O2S
    7-[chloro(difluoro)methyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-{3-cyano-4H,5H,6H,7H,8H-cyclohepta[B]thiophen-2-YL}-5-(furan-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C22H16ClF2N5O2S
    7-(Chlorodifluoromethyl)-N-{3-cyano-4H,5H,6H,7H,8H-cyclohepta[B]thiophen-2-YL}-5-(furan-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(4-fluorophenyl)-1,3-dimethyl-8-(2-methylphenyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione —— C22H18FN5O2
    7-(4-fluorophenyl)-1,3-dimethyl-8-(2-methylphenyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
    —— 7-[(3,4-Diethoxyphenyl)methyl]-8-{[(2-fluorophenyl)methyl]sulfanyl}-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione —— C25H27FN4O4S
    7-[(3,4-Diethoxyphenyl)methyl]-8-{[(2-fluorophenyl)methyl]sulfanyl}-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
    —— 7-(difluoromethyl)-N-methyl-5-(4-methylphenyl)-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H17F5N4O2
    7-(difluoromethyl)-N-methyl-5-(4-methylphenyl)-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(4-{[(2-Bromophenyl)carbonyl]carbamothioyl}piperazin-1-ium-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate —— C24H22BrFN4O4S
    7-(4-{[(2-Bromophenyl)carbonyl]carbamothioyl}piperazin-1-ium-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
    —— 7-(3-Methoxyphenyl)-1-phenyl-5,5-bis(trifluoromethyl)-1H,2H,3H,4H,5H,8H-pyrimido[4,5-D][1,3]diazine-2,4-dione —— C21H14F6N4O3
    7-(3-Methoxyphenyl)-1-phenyl-5,5-bis(trifluoromethyl)-1H,2H,3H,4H,5H,8H-pyrimido[4,5-D][1,3]diazine-2,4-dione
    —— 7-(4-Chlorophenyl)-1,3-dimethyl-8-propyl-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione —— C18H18ClN5O2
    7-(4-Chlorophenyl)-1,3-dimethyl-8-propyl-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione
    —— 7-Benzyl-1-(4-methoxyphenyl)-5,5-bis(trifluoromethyl)-1H,2H,3H,4H,5H,8H-pyrimido[4,5-D][1,3]diazine-2,4-dione —— C22H16F6N4O3
    7-Benzyl-1-(4-methoxyphenyl)-5,5-bis(trifluoromethyl)-1H,2H,3H,4H,5H,8H-pyrimido[4,5-D][1,3]diazine-2,4-dione
    —— (7S)-4-(2-methoxy-4-prop-2-enylphenoxy)-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine —— C21H22N2O2S
    (7S)-4-(2-methoxy-4-prop-2-enylphenoxy)-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
    —— 7-[(S)-(4-methoxyanilino)-pyridin-2-ylmethyl]quinolin-8-ol —— C22H19N3O2
    7-[(S)-(4-methoxyanilino)-pyridin-2-ylmethyl]quinolin-8-ol
    —— 7-Benzyl-3-methyl-1-[(2-methylphenyl)methyl]-2,3,6,7-tetrahydro-1H-purine-2,6-dione —— C21H20N4O2
    7-Benzyl-3-methyl-1-[(2-methylphenyl)methyl]-2,3,6,7-tetrahydro-1H-purine-2,6-dione
    —— 7-(Chlorodifluoromethyl)-N-(2,5-difluorophenyl)-5-(furan-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C18H9ClF4N4O2
    7-(Chlorodifluoromethyl)-N-(2,5-difluorophenyl)-5-(furan-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-(5-methyl-1,2-oxazol-3-YL)-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C16H10ClF2N5O2S
    7-(Chlorodifluoromethyl)-N-(5-methyl-1,2-oxazol-3-YL)-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-Benzyl-4-methoxymethyl-2-methyl-7H-9-thia-1,5,6,7-tetraaza-fluoren-8-one —— C18H16N4O2S
    7-Benzyl-4-methoxymethyl-2-methyl-7H-9-thia-1,5,6,7-tetraaza-fluoren-8-one
    —— 7-[(R)-(4-methoxyanilino)-pyridin-2-ylmethyl]quinolin-8-ol —— C22H19N3O2
    7-[(R)-(4-methoxyanilino)-pyridin-2-ylmethyl]quinolin-8-ol
    —— 7-(4-fluorophenyl)-1,3-dimethyl-8-(3-methylphenyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione —— C22H18FN5O2
    7-(4-fluorophenyl)-1,3-dimethyl-8-(3-methylphenyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
    —— 7-(4-bromophenyl)-6-[(2S)-2-hydroxy-2-phenylethyl]-2,4-dimethylpurino[7,8-a]imidazole-1,3-dione —— C23H20BrN5O3
    7-(4-bromophenyl)-6-[(2S)-2-hydroxy-2-phenylethyl]-2,4-dimethylpurino[7,8-a]imidazole-1,3-dione
    —— 7-(4-Bromophenyl)-1,3-dimethyl-8-[4-(trifluoromethoxy)phenyl]-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione —— C22H15BrF3N5O3
    7-(4-Bromophenyl)-1,3-dimethyl-8-[4-(trifluoromethoxy)phenyl]-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione
    —— 7-(Chlorodifluoromethyl)-N-(2,4-difluorophenyl)-5-(furan-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C18H9ClF4N4O2
    7-(Chlorodifluoromethyl)-N-(2,4-difluorophenyl)-5-(furan-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(4-bromophenyl)-6-[(2R)-2-hydroxy-2-phenylethyl]-2,4-dimethylpurino[7,8-a]imidazole-1,3-dione —— C23H20BrN5O3
    7-(4-bromophenyl)-6-[(2R)-2-hydroxy-2-phenylethyl]-2,4-dimethylpurino[7,8-a]imidazole-1,3-dione
    —— 7-(4-fluorophenyl)-8-(4-methoxyphenyl)-1,3-dimethyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione —— C22H18FN5O3
    7-(4-fluorophenyl)-8-(4-methoxyphenyl)-1,3-dimethyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
    —— 7-[2-(4-Methoxyphenyl)-2-oxoethyl]-1,3-dimethyl-8-(4-methylpiperazin-1-YL)-2,3,6,7-tetrahydro-1H-purine-2,6-dione —— C21H26N6O4
    7-[2-(4-Methoxyphenyl)-2-oxoethyl]-1,3-dimethyl-8-(4-methylpiperazin-1-YL)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
    —— 7-Benzyl-1-[(3-iodophenyl)methyl]-3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione —— C20H17IN4O2
    7-Benzyl-1-[(3-iodophenyl)methyl]-3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
    —— 7-(Chlorodifluoromethyl)-5-(furan-2-YL)-N-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C19H10ClF5N4O2
    7-(Chlorodifluoromethyl)-5-(furan-2-YL)-N-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-5-(furan-2-YL)-N-[2-(1H-indol-3-YL)ethyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C22H16ClF2N5O2
    7-(Chlorodifluoromethyl)-5-(furan-2-YL)-N-[2-(1H-indol-3-YL)ethyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-5-(furan-2-YL)-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C19H10ClF5N4O3
    7-(Chlorodifluoromethyl)-5-(furan-2-YL)-N-[4-(trifluoromethoxy)phenyl]pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-(Chlorodifluoromethyl)-N-[2-(5-methoxy-2-methyl-1H-indol-3-YL)ethyl]-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide —— C24H20ClF2N5O2S
    7-(Chlorodifluoromethyl)-N-[2-(5-methoxy-2-methyl-1H-indol-3-YL)ethyl]-5-(thiophen-2-YL)pyrazolo[1,5-A]pyrimidine-2-carboxamide
    —— 7-Benzyl-1-[(4-tert-butylphenyl)methyl]-3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione —— C24H26N4O2
    7-Benzyl-1-[(4-tert-butylphenyl)methyl]-3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
    —— 7-(4-Methoxyphenyl)-1,3-dimethyl-8-[3-(trifluoromethyl)phenyl]-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione —— C23H18F3N5O3
    7-(4-Methoxyphenyl)-1,3-dimethyl-8-[3-(trifluoromethyl)phenyl]-1H,2H,3H,4H,8H-imidazo[1,2-G]purine-2,4-dione