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    —— (7S)-2-[2-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-2-oxoethyl]sulfanyl-7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C20H27N3O2S2
    (7S)-2-[2-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-2-oxoethyl]sulfanyl-7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-(2-morpholin-4-yl-2-oxoethyl)sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C20H27N3O3S2
    (7R)-7-tert-butyl-2-(2-morpholin-4-yl-2-oxoethyl)sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-(2-oxo-2-pyrrolidin-1-ylethyl)sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C20H27N3O2S2
    (7R)-7-tert-butyl-2-(2-oxo-2-pyrrolidin-1-ylethyl)sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-methyl-2-[2-[(2S)-2-methylpiperidin-1-yl]-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C19H25N3O2S2
    (7S)-7-methyl-2-[2-[(2S)-2-methylpiperidin-1-yl]-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-methyl-2-[2-[(2S)-2-methyl-2,3-dihydroindol-1-yl]-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H23N3O2S2
    (7S)-7-methyl-2-[2-[(2S)-2-methyl-2,3-dihydroindol-1-yl]-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-methyl-2-(2-oxo-2-pyrrolidin-1-ylethyl)sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C17H21N3O2S2
    (7R)-7-methyl-2-(2-oxo-2-pyrrolidin-1-ylethyl)sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-methyl-2-[2-[(2R)-2-methyl-2,3-dihydroindol-1-yl]-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H23N3O2S2
    (7S)-7-methyl-2-[2-[(2R)-2-methyl-2,3-dihydroindol-1-yl]-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-methyl-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C19H25N3O2S2
    (7S)-7-methyl-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-methyl-2-[2-[(2R)-2-methyl-2,3-dihydroindol-1-yl]-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H23N3O2S2
    (7R)-7-methyl-2-[2-[(2R)-2-methyl-2,3-dihydroindol-1-yl]-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-methyl-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C19H25N3O2S2
    (7R)-7-methyl-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-methyl-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C18H23N3O2S2
    (7R)-7-methyl-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-2-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]sulfanyl-7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H23N3O2S2
    (7R)-2-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethyl]sulfanyl-7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-[(4-propanoylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H32N4O2S
    (7R)-7-tert-butyl-2-[(4-propanoylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-[[4-(2-fluorobenzoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C26H31FN4O2S
    (7R)-7-tert-butyl-2-[[4-(2-fluorobenzoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-2-[(4-benzoylpiperazin-1-yl)methyl]-7-tert-butyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C26H32N4O2S
    (7S)-2-[(4-benzoylpiperazin-1-yl)methyl]-7-tert-butyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-tert-butyl-2-[[4-(2-methylpropanoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C23H34N4O2S
    (7S)-7-tert-butyl-2-[[4-(2-methylpropanoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-[[4-(2-methylpropanoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C23H34N4O2S
    (7R)-7-tert-butyl-2-[[4-(2-methylpropanoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-[[4-(3-fluorobenzoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C26H31FN4O2S
    (7R)-7-tert-butyl-2-[[4-(3-fluorobenzoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-tert-butyl-2-[[4-(3-fluorobenzoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C26H31FN4O2S
    (7S)-7-tert-butyl-2-[[4-(3-fluorobenzoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-[(4-ethylsulfonylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C21H32N4O3S2
    (7R)-7-tert-butyl-2-[(4-ethylsulfonylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-[[4-(4-methoxybenzoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C27H34N4O3S
    (7R)-7-tert-butyl-2-[[4-(4-methoxybenzoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-[[4-(cyclobutanecarbonyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C24H34N4O2S
    (7R)-7-tert-butyl-2-[[4-(cyclobutanecarbonyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-tert-butyl-2-[(4-propanoylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H32N4O2S
    (7S)-7-tert-butyl-2-[(4-propanoylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-2-[(4-butanoylpiperazin-1-yl)methyl]-7-tert-butyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C23H34N4O2S
    (7R)-2-[(4-butanoylpiperazin-1-yl)methyl]-7-tert-butyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-2-[(4-acetylpiperazin-1-yl)methyl]-7-tert-butyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C21H30N4O2S
    (7R)-2-[(4-acetylpiperazin-1-yl)methyl]-7-tert-butyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-2-[(4-butanoylpiperazin-1-yl)methyl]-7-tert-butyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C23H34N4O2S
    (7S)-2-[(4-butanoylpiperazin-1-yl)methyl]-7-tert-butyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7R)-7-tert-butyl-2-[[4-(2,2-dimethylpropanoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C24H36N4O2S
    (7R)-7-tert-butyl-2-[[4-(2,2-dimethylpropanoyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-tert-butyl-2-[(4-methylsulfonylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C20H30N4O3S2
    (7S)-7-tert-butyl-2-[(4-methylsulfonylpiperazin-1-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-tert-butyl-2-[[4-(cyclobutanecarbonyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C24H34N4O2S
    (7S)-7-tert-butyl-2-[[4-(cyclobutanecarbonyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-7-tert-butyl-2-[[4-(cyclopropanecarbonyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C23H32N4O2S
    (7S)-7-tert-butyl-2-[[4-(cyclopropanecarbonyl)piperazin-1-yl]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— 7,16-Dithia-3,12-diazapentacyclo[10.6.0.03,10.04,8.013,17]octadeca-1(18),4(8),5,9,13(17),14-hexaene-2,11-dione —— C14H6N2O2S2
    7,16-Dithia-3,12-diazapentacyclo[10.6.0.03,10.04,8.013,17]octadeca-1(18),4(8),5,9,13(17),14-hexaene-2,11-dione
    —— 7-[(4-Chlorophenyl)methyl]-1,3-dimethyl-8-(2-oxo-2-piperidin-1-ylethyl)sulfanylpurine-2,6-dione —— C21H24ClN5O3S
    7-[(4-Chlorophenyl)methyl]-1,3-dimethyl-8-(2-oxo-2-piperidin-1-ylethyl)sulfanylpurine-2,6-dione
    —— 7-[(4-Fluorophenyl)methyl]-1,3-dimethyl-8-[2-oxo-2-(2,3,5,6-tetramethylphenyl)ethyl]sulfanylpurine-2,6-dione —— C26H27FN4O3S
    7-[(4-Fluorophenyl)methyl]-1,3-dimethyl-8-[2-oxo-2-(2,3,5,6-tetramethylphenyl)ethyl]sulfanylpurine-2,6-dione
    —— 7,8-dimethyl-3-[(S)-[1-(2-phenylethyl)tetrazol-5-yl]-thiomorpholin-4-ylmethyl]-1H-quinolin-2-one —— C25H28N6OS
    7,8-dimethyl-3-[(S)-[1-(2-phenylethyl)tetrazol-5-yl]-thiomorpholin-4-ylmethyl]-1H-quinolin-2-one
    —— 7,8-dimethyl-3-[(R)-[1-(2-phenylethyl)tetrazol-5-yl]-thiomorpholin-4-ylmethyl]-1H-quinolin-2-one —— C25H28N6OS
    7,8-dimethyl-3-[(R)-[1-(2-phenylethyl)tetrazol-5-yl]-thiomorpholin-4-ylmethyl]-1H-quinolin-2-one
    —— 7-[(S)-morpholin-4-yl-[1-(2-phenylethyl)tetrazol-5-yl]methyl]-5H-[1,3]dioxolo[4,5-g]quinolin-6-one —— C24H24N6O4
    7-[(S)-morpholin-4-yl-[1-(2-phenylethyl)tetrazol-5-yl]methyl]-5H-[1,3]dioxolo[4,5-g]quinolin-6-one
    —— 7,8-Dimethyl-2-(4-methylsulfonylpiperazin-1-yl)quinoline-3-carbonitrile —— C17H20N4O2S
    7,8-Dimethyl-2-(4-methylsulfonylpiperazin-1-yl)quinoline-3-carbonitrile
    —— 7-Methoxy-2-[4-[(2-methylphenyl)-oxomethyl]-1-piperazinyl]-3-quinolinecarbonitrile —— C23H22N4O2
    7-Methoxy-2-[4-[(2-methylphenyl)-oxomethyl]-1-piperazinyl]-3-quinolinecarbonitrile
    —— 7-Methoxy-2-[4-(pyridine-4-carbonyl)piperazin-1-yl]quinoline-3-carbonitrile —— C21H19N5O2
    7-Methoxy-2-[4-(pyridine-4-carbonyl)piperazin-1-yl]quinoline-3-carbonitrile
    —— 7-Methoxy-2-[4-(4-methylbenzoyl)piperazin-1-yl]quinoline-3-carbonitrile —— C23H22N4O2
    7-Methoxy-2-[4-(4-methylbenzoyl)piperazin-1-yl]quinoline-3-carbonitrile
    —— 7-Methyl-2-(4-propanoylpiperazin-1-yl)quinoline-3-carbonitrile —— C18H20N4O
    7-Methyl-2-(4-propanoylpiperazin-1-yl)quinoline-3-carbonitrile
    —— 7-ethyl-2-[(3R)-3-hydroxypiperidin-1-yl]quinoline-3-carbonitrile —— C17H19N3O
    7-ethyl-2-[(3R)-3-hydroxypiperidin-1-yl]quinoline-3-carbonitrile
    —— 7-ethyl-2-[(3S)-3-hydroxypiperidin-1-yl]quinoline-3-carbonitrile —— C17H19N3O
    7-ethyl-2-[(3S)-3-hydroxypiperidin-1-yl]quinoline-3-carbonitrile
    —— 7-Methyl-2-[4-(3,4,5-trimethoxybenzoyl)piperazin-1-yl]quinoline-3-carbonitrile —— C25H26N4O4
    7-Methyl-2-[4-(3,4,5-trimethoxybenzoyl)piperazin-1-yl]quinoline-3-carbonitrile
    —— 7,8-Dimethyl-2-(4-propanoylpiperazin-1-yl)quinoline-3-carbonitrile —— C19H22N4O
    7,8-Dimethyl-2-(4-propanoylpiperazin-1-yl)quinoline-3-carbonitrile
    —— 7-Ethyl-2-(4-hydroxypiperidin-1-yl)quinoline-3-carbonitrile —— C17H19N3O
    7-Ethyl-2-(4-hydroxypiperidin-1-yl)quinoline-3-carbonitrile
    —— 7-Methoxy-2-[4-(2-thienylcarbonyl)-1-piperazinyl]-3-quinolinecarbonitrile —— C20H18N4O2S
    7-Methoxy-2-[4-(2-thienylcarbonyl)-1-piperazinyl]-3-quinolinecarbonitrile
    —— 7-ethoxy-N-methyl-3-[[(2R)-oxolan-2-yl]methyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imine —— C19H23N3O2S
    7-ethoxy-N-methyl-3-[[(2R)-oxolan-2-yl]methyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imine
    —— 7-ethoxy-N-ethyl-3-[[(2S)-oxolan-2-yl]methyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imine —— C20H25N3O2S
    7-ethoxy-N-ethyl-3-[[(2S)-oxolan-2-yl]methyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imine
    —— 7-ethoxy-N-methyl-3-[[(2S)-oxolan-2-yl]methyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imine —— C19H23N3O2S
    7-ethoxy-N-methyl-3-[[(2S)-oxolan-2-yl]methyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imine