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    —— 7-(difluoromethyl)-N-[(1-ethyl-1H-pyrazol-4-yl)methyl]-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C21H20F2N6O
    7-(difluoromethyl)-N-[(1-ethyl-1H-pyrazol-4-yl)methyl]-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2R)-2-methyl-2,3-dihydroindol-1-yl]methanone —— C24H20F2N4O
    [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2R)-2-methyl-2,3-dihydroindol-1-yl]methanone
    —— 7-(difluoromethyl)-5-(4-methylphenyl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C21H17F2N5O
    7-(difluoromethyl)-5-(4-methylphenyl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-(2-fluoro-5-methylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C15H12F3N5O
    7-(difluoromethyl)-N-(2-fluoro-5-methylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl](2,3-dihydro-1H-indol-1-yl)methanone —— C23H18F2N4O
    [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl](2,3-dihydro-1H-indol-1-yl)methanone
    —— 7-(difluoromethyl)-N-methyl-5-(4-methylphenyl)-N-[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H24F2N6O
    7-(difluoromethyl)-N-methyl-5-(4-methylphenyl)-N-[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— [7-(Difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-A]pyrimidin-3-YL](4-methylpiperidino)methanone —— C21H22F2N4O
    [7-(Difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-A]pyrimidin-3-YL](4-methylpiperidino)methanone
    —— 7-(difluoromethyl)-N-[(2R)-1-methoxypropan-2-yl]-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H18F2N4O2
    7-(difluoromethyl)-N-[(2R)-1-methoxypropan-2-yl]-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-[(1,5-dimethyl-1H-pyrazol-4-yl)methyl]-N-methyl-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H22F2N6O
    7-(difluoromethyl)-N-[(1,5-dimethyl-1H-pyrazol-4-yl)methyl]-N-methyl-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(2R)-2-ethylpiperidin-1-yl]methanone —— C21H22F2N4O
    [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(2R)-2-ethylpiperidin-1-yl]methanone
    —— 7-(difluoromethyl)-N-(1,3-dimethyl-1H-pyrazol-4-yl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H18F2N6O
    7-(difluoromethyl)-N-(1,3-dimethyl-1H-pyrazol-4-yl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-(3,4-dimethoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H18F2N4O3
    7-(difluoromethyl)-N-(3,4-dimethoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-[(1,3-dimethyl-1H-pyrazol-4-yl)methyl]-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C21H20F2N6O
    7-(difluoromethyl)-N-[(1,3-dimethyl-1H-pyrazol-4-yl)methyl]-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2S,6S)-2,6-dimethylmorpholin-4-yl]methanone —— C21H22F2N4O2
    [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2S,6S)-2,6-dimethylmorpholin-4-yl]methanone
    —— [7-(Difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-A]pyrimidin-3-YL](1-pyrrolidinyl)methanone —— C19H18F2N4O
    [7-(Difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-A]pyrimidin-3-YL](1-pyrrolidinyl)methanone
    —— [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2S)-2-methyl-2,3-dihydroindol-1-yl]methanone —— C24H20F2N4O
    [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2S)-2-methyl-2,3-dihydroindol-1-yl]methanone
    —— [7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone —— C24H20F2N4O2
    [7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
    —— 7-(difluoromethyl)-N-[(1,5-dimethyl-1H-pyrazol-4-yl)methyl]-N-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide —— C21H20F2N6O
    7-(difluoromethyl)-N-[(1,5-dimethyl-1H-pyrazol-4-yl)methyl]-N-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-[[(2R)-oxolan-2-yl]methyl]-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H18F2N4O2
    7-(difluoromethyl)-N-[[(2R)-oxolan-2-yl]methyl]-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-(3,4-dimethoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C16H15F2N5O3
    7-(difluoromethyl)-N-(3,4-dimethoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— (7-Difluoromethyl-5-p-tolyl-pyrazolo[1,5-a]pyrimidin-3-yl)-(3,4-dihydro-2H-quinolin-1-yl)-methanone —— C24H20F2N4O
    (7-Difluoromethyl-5-p-tolyl-pyrazolo[1,5-a]pyrimidin-3-yl)-(3,4-dihydro-2H-quinolin-1-yl)-methanone
    —— 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N~3~-(5-methyl-3-isoxazolyl)pyrazolo[1,5-A]pyrimidine-3-carboxamide —— C19H15F2N5O3
    7-(Difluoromethyl)-5-(4-methoxyphenyl)-N~3~-(5-methyl-3-isoxazolyl)pyrazolo[1,5-A]pyrimidine-3-carboxamide
    —— [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(3R)-3-methylpiperidin-1-yl]methanone —— C20H20F2N4O
    [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(3R)-3-methylpiperidin-1-yl]methanone
    —— 7-(Difluoromethyl)-5-phenyl-3-[(4-pyridin-2-ylpiperazin-1-yl)carbonyl]pyrazolo[1,5-a]pyrimidine —— C23H20F2N6O
    7-(Difluoromethyl)-5-phenyl-3-[(4-pyridin-2-ylpiperazin-1-yl)carbonyl]pyrazolo[1,5-a]pyrimidine
    —— [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(2S,6R)-2,6-dimethylmorpholin-4-yl]methanone —— C20H20F2N4O2
    [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(2S,6R)-2,6-dimethylmorpholin-4-yl]methanone
    —— [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(2R,6R)-2,6-dimethylmorpholin-4-yl]methanone —— C20H20F2N4O2
    [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(2R,6R)-2,6-dimethylmorpholin-4-yl]methanone
    —— [7-(Difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-A]pyrimidin-3-YL][4-(2-pyrimidinyl)piperazino]methanone —— C23H21F2N7O
    [7-(Difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-A]pyrimidin-3-YL][4-(2-pyrimidinyl)piperazino]methanone
    —— 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H15F2N5O2
    7-(difluoromethyl)-5-(4-methoxyphenyl)-N-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— [7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(3R)-3-methylpiperidin-1-yl]methanone —— C21H22F2N4O2
    [7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(3R)-3-methylpiperidin-1-yl]methanone
    —— 7-(difluoromethyl)-N-[1-(4-fluorobenzyl)-1H-pyrazol-4-yl]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C18H14F3N7O
    7-(difluoromethyl)-N-[1-(4-fluorobenzyl)-1H-pyrazol-4-yl]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2S)-2-methylpiperidin-1-yl]methanone —— C21H22F2N4O
    [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2S)-2-methylpiperidin-1-yl]methanone
    —— 7-(Difluoromethyl)-N-{3,5-dimethyl-1-[(4-methylphenyl)methyl]-1H-pyrazol-4-YL}-5-methyl-[1,2,4]triazolo[1,5-A]pyrimidine-2-carboxamide —— C21H21F2N7O
    7-(Difluoromethyl)-N-{3,5-dimethyl-1-[(4-methylphenyl)methyl]-1H-pyrazol-4-YL}-5-methyl-[1,2,4]triazolo[1,5-A]pyrimidine-2-carboxamide
    —— [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(2S)-2-ethylpiperidin-1-yl]methanone —— C21H22F2N4O
    [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-[(2S)-2-ethylpiperidin-1-yl]methanone
    —— 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[(2R)-1-methoxypropan-2-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H20F2N4O3
    7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[(2R)-1-methoxypropan-2-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-(4-ethylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C16H15F2N5O
    7-(difluoromethyl)-N-(4-ethylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— 7-(Difluoromethyl)-5-methyl-N-[4-(propan-2-YL)phenyl]-[1,2,4]triazolo[1,5-A]pyrimidine-2-carboxamide —— C17H17F2N5O
    7-(Difluoromethyl)-5-methyl-N-[4-(propan-2-YL)phenyl]-[1,2,4]triazolo[1,5-A]pyrimidine-2-carboxamide
    —— [7-(Difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-A]pyrimidin-3-YL](4-methylpiperidino)methanone —— C21H22F2N4O2
    [7-(Difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-A]pyrimidin-3-YL](4-methylpiperidino)methanone
    —— 7-(Difluoromethyl)-N~3~-(4-hydroxyphenyl)-5-(4-methylphenyl)pyrazolo[1,5-A]pyrimidine-3-carboxamide —— C21H16F2N4O2
    7-(Difluoromethyl)-N~3~-(4-hydroxyphenyl)-5-(4-methylphenyl)pyrazolo[1,5-A]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-5-methyl-N-naphthalen-1-yl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C18H13F2N5O
    7-(difluoromethyl)-5-methyl-N-naphthalen-1-yl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— 7-(difluoromethyl)-5-phenyl-N-[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C21H20F2N6O
    7-(difluoromethyl)-5-phenyl-N-[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-(3,4-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C14H9F4N5O
    7-(difluoromethyl)-N-(3,4-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[(1S)-1-[(2S)-oxolan-2-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C21H22F2N4O3
    7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[(1S)-1-[(2S)-oxolan-2-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-(difluoromethyl)-N-(4-fluoro-2-methylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C15H12F3N5O
    7-(difluoromethyl)-N-(4-fluoro-2-methylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— [7-(Difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-A]pyrimidin-3-YL][3,4-dihydro-2(1H)-isoquinolinyl]methanone —— C24H20F2N4O2
    [7-(Difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-A]pyrimidin-3-YL][3,4-dihydro-2(1H)-isoquinolinyl]methanone
    —— 7-(difluoromethyl)-5-methyl-N-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C17H17F2N5O4
    7-(difluoromethyl)-5-methyl-N-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2R)-2-methylpiperidin-1-yl]methanone —— C21H22F2N4O
    [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2R)-2-methylpiperidin-1-yl]methanone
    —— 7-(difluoromethyl)-N-(2,3-dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide —— C16H15F2N5O
    7-(difluoromethyl)-N-(2,3-dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide
    —— 7-(Difluoromethyl)-5-(4-methylphenyl)-3-[(4-pyridin-2-ylpiperazin-1-yl)carbonyl]pyrazolo[1,5-a]pyrimidine —— C24H22F2N6O
    7-(Difluoromethyl)-5-(4-methylphenyl)-3-[(4-pyridin-2-ylpiperazin-1-yl)carbonyl]pyrazolo[1,5-a]pyrimidine
    —— [7-Difluoromethyl-5-(4-methoxy-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone —— C20H21F2N5O2
    [7-Difluoromethyl-5-(4-methoxy-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone
    —— 7-(Difluoromethyl)-5-(4-methylphenyl)-N~3~-(2-morpholinoethyl)pyrazolo[1,5-A]pyrimidine-3-carboxamide —— C21H23F2N5O2
    7-(Difluoromethyl)-5-(4-methylphenyl)-N~3~-(2-morpholinoethyl)pyrazolo[1,5-A]pyrimidine-3-carboxamide