喜树碱
相关化合物
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| —— | [(19S)-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl] 2-[4-(2-hydroxyethyl)piperazin-1-yl]acetate | —— | C28H30N4O6 |
| —— | Camptothecin, 20-O-(1-piperazino)acetyl-2hcl | —— | C26H27ClN4O5 |
| —— | [(19S)-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl] 2-[4-(2-hydroxyethyl)piperazin-1-yl]acetate;dihydrochloride | —— | C28H32Cl2N4O6 |
| —— | Sodium (R)-2-hydroxy-2-(8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)butanoate | —— | C20H17N2NaO5 |
| —— | (R)-4-Ethyl-4-hydroxy-10-methoxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione | —— | C21H18N2O5 |
| —— | (19R)-19-ethyl-19-hydroxy-7-methoxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione | —— | C21H18N2O5 |
| —— | [(19R)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-aminopiperidine-1-carboxylate | —— | C28H30N4O6 |
| —— | (19R)-6,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione | —— | C22H20N2O4 |
| —— | 19-ethyl-19-hydroxy-10-[[4-[[9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]amino]phenyl]iminomethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione | —— | C48H40N4O11 |
| —— | 19-ethyl-19-hydroxy-10-[[2-[[9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]amino]phenyl]iminomethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione | —— | C48H40N4O11 |
| —— | 19-Ethyl-19-hydroxy-3-oxido-17-oxa-13-aza-3-azoniapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione | —— | C20H16N2O5 |
| —— | SN38 glucuronide;SN 38 glucuronide;SN-38G | —— | C28H28N2O11 |
| —— | 2-[12-ethyl-8-(hydroxymethyl)-9-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)oxy-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate | —— | C33H39N4O7- |
| —— | 2-[12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate | —— | C22H21N2O6- |
| —— | 2-[2-(6-carboxy-3,4,5-trihydroxyoxan-2-yl)oxy-12-ethyl-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate | —— | C28H29N2O12- |
| —— | N'-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]oxamide | —— | C23H19N5O6 |
| —— | N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]pyrrolidine-2-carboxamide | —— | C26H25N5O5 |
| —— | 2-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]-3-(1H-indol-3-yl)propanamide | —— | C32H28N6O5 |
| —— | Ethyl 2-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl)oxy]acetate | —— | C24H22N2O7 |
| —— | (19R)-19-hydroxy-10-methoxy-19-(2-morpholin-4-yl-2-oxoethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione | —— | C25H23N3O7 |
| —— | (19R)-19-ethyl-19-hydroxy-10-methoxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione | —— | C21H18N2O5 |
| —— | (19S)-19-hydroxy-10-methoxy-19-(2-morpholin-4-yl-2-oxoethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione | —— | C25H23N3O7 |
| —— | Camptothecinethylglycinate esterhydrochloride | —— | C24H24ClN3O5 |
| —— | Camptothecin,20-O-((4-(2-hydroxyethyl)-1-piperazino)oac | —— | C28H30N4O6 |
| —— | N'-[[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl]methylideneamino]oxamide;hydrochloride | —— | C23H20ClN5O6 |
| —— | N-[[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl]methylideneamino]pyrrolidine-2-carboxamide;hydrochloride | —— | C26H26ClN5O5 |
| —— | 2-amino-N-[[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl]methylideneamino]-4-methylpentanamide;hydrochloride | —— | C27H30ClN5O5 |
| —— | (19-Ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl) 2,6-diaminohexanoate;hydrochloride | —— | C26H29ClN4O5 |
| —— | 19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),4,7,9,15(20)-hexaene-6,14,18-trione | —— | C20H16N2O6 |
| —— | 2-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]-3-methylpentanamide | —— | C27H29N5O5 |
| —— | 2-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]-3-(4-hydroxyphenyl)propanamide | —— | C30H27N5O6 |
| —— | 2-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]-4-methylpentanamide | —— | C27H29N5O5 |
| —— | [(19R)-8-amino-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl] 2-(dimethylamino)acetate | —— | C24H24N4O5 |
| —— | [(19R)-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl] 2-(dimethylamino)acetate | —— | C24H23N3O5 |
| —— | [(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-[[2-[2-[2-[[4-[[4-[3,5-bis[[bis(pyridin-2-ylmethyl)amino]methyl]phenoxy]butyl-[1-(4-chlorophenyl)cyclohexanecarbonyl]amino]methyl]benzoyl]amino]ethoxy]ethoxy]ethyl-[1-(4-chlorophenyl)cyclohexanecarbonyl]amino]methyl]benzoate | —— | C106H111Cl2N11O12 |
| —— | 7,19-Dihydroxy-19-propyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione | —— | C21H18N2O5 |
| —— | 4-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]benzamide | —— | C28H23N5O5 |
| —— | 2-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]propanamide | —— | C24H23N5O5 |
| —— | 2-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]-3-(1H-imidazol-5-yl)propanamide | —— | C27H25N7O5 |
| —— | N-[(E)-(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]-2-pyridin-1-ium-1-ylacetamide | —— | C28H24N5O5+ |
| —— | 2-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]-4-methylsulfanylbutanamide | —— | C26H27N5O5S |
| —— | 5-[[1-[(10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl)oxycarbonyl]piperidin-4-yl]amino]pentanoic acid;hydrochloride | —— | C33H39ClN4O8 |
| —— | Methyl 3,4,5-triacetyloxy-6-[(10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl)oxy]oxane-2-carboxylate | —— | C35H36N2O14 |
| —— | SN-38 glucuronide-13C6 | —— | C28H28N2O11 |
| —— | 2-amino-N-[(19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-10-yl)methylideneamino]-3-sulfanylpropanamide | —— | C24H23N5O5S |
| —— | (20S)-disodium 2-hydroxy-2-(3-hydroxymethyl-9-olato-4-oxo-4,6-dihydroindolizino[1,2-b]quinolin-2-yl)butanoate | —— | C20H16N2O6-2 |
| —— | (20RS)-Sodium; 2-(1-amino-8-hydroxymethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-7-yl)-2-hydroxy-butyrate | —— | C20H18N3O5- |
| —— | (20R)-sodium 2-(13-amino-8-hydroxymethyl-9-oxo-9,11-dihydro[1,3]dioxolo[5,4-g]indolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoate | —— | C21H18N3O7- |
| —— | (20RS)-sodium 2-hydroxy-2-(8-hydroxymethyl-9-oxo-9,11-dihydro[1,3]dioxolo[5,4-g]indolizino[1,2-b]quinolin-7-yl)butanoate | —— | C21H17N2O7- |
| —— | (2S)-2-hydroxy-2-[7-(hydroxymethyl)-8-oxo-16,18-dioxa-2,9-diazapentacyclo[11.7.0.03,11.04,9.015,19]icosa-1,3(11),4,6,12,14,19-heptaen-6-yl]butanoate | —— | C21H17N2O7- |
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