| 880145-70-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• CAS: 880145-70-0
• 化学式: C₅₀H₅₆N₂O₁₂
• 分子量: 877.001
• InChiKey: LKJKFEUKDYLUSC-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  、 2-氰乙基N,N-二异丙基氯亚磷酰胺 在 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 以94%的产率得到
  参考文献：
  名称：

  Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein

  摘要：

  The synthesis of triplexes possessing an anthraquinonyl roup and composed of branched oligonucleotides (ONs) is described. Binding ability of a triplex-binding protein (MBP-LOR3(ARF)) to the triplexes was evaluated by an electrophoretic mobility shift assay (EMSA). It was found that the triplex, which has an anthraquinonecarbonyl group at the 5'-end of the third strand and is connected with the pentaerythritol linker, has greater affinity to the protein than an unmodified triplex. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.036
• 作为产物：
  描述：

  在 吡啶 、 一水合肼 、 溶剂黄146 作用下， 以81%的产率得到
  参考文献：
  名称：

  Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein

  摘要：

  The synthesis of triplexes possessing an anthraquinonyl roup and composed of branched oligonucleotides (ONs) is described. Binding ability of a triplex-binding protein (MBP-LOR3(ARF)) to the triplexes was evaluated by an electrophoretic mobility shift assay (EMSA). It was found that the triplex, which has an anthraquinonecarbonyl group at the 5'-end of the third strand and is connected with the pentaerythritol linker, has greater affinity to the protein than an unmodified triplex. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.036