dichloro-bis(piperidine)-platinum(II) | 35963-87-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: dichloro-bis(piperidine)-platinum(II)
• 英文别名: [PtCl2(piperidine)2]；dichloroplatinum;piperidine
• CAS: 35963-87-2
• 化学式: C₁₀H₂₂Cl₂N₂Pt
• 分子量: 436.284
• InChiKey: RCASKFJJJBDKAL-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  potassium cyanide 、 dichloro-bis(piperidine)-platinum(II) 以 甲醇 、 水 为溶剂， 生成 {Pt(piperidine)(CN)3}(1-)
  参考文献：
  名称：

  The cis- and trans-effects of cyanide in substitution at platinum(II)

  摘要：

  The cis- and trans-[Pt(am)2Cl2] isomers (am = dimethylamine, pyridine, 4-cyanopyridine, 4-chloropyridine, 2-methylpyridine, 4-methylpyridine, 2,4-dimethylpyridine, 4-ethylpyridine, morpholine or piperidine), react rapidly with excess CN- in methanol to form the corresponding cis- and trans-[Pt(am)2(CN)2] species which then react further to give [Pt(CN)4]2-. The kinetics of the slow step, [Pt(am)2(CN)2] + CN- --> [Pt(am)(CN)3]- + am, has been studied. In spite of the strong trans effect of CN- the trans species are all more reactive than the corresponding cis isomers. The second-order rate constants are sensitive to the nature of am; plots of log k2 against the pK(a) of Ham+ are linear but the slope for the trans isomers (-0.27) is much greater than that for the cis isomers (-0.07). The rate constants for the displacement of o-methyl substituted pyridines are smaller than predicted from their basicity. This steric hindrance effect is much more marked in the trans isomers. The complexes with am = NH3 and NH2Me are similarly less reactive than might be predicted but the effect is the same in both isomers. The results are explained in terms of the trans effect of cyanide and its effect upon the intrinsic reactivities and nucleophilic discriminations of the substrates.

  DOI：

  10.1039/dt9930000233
• 作为产物：
  描述：

  (piperidinium)2 chloroplatinate(II) 以 solid 为溶剂， 生成 dichloro-bis(piperidine)-platinum(II)
  参考文献：
  名称：

  Kukushkin, Yu. N.; Sedova, G. N.; Belyaev, A. N., Russian Journal of Inorganic Chemistry, 1978, vol. 23, p. 1165 - 1167

  摘要：

  DOI：

文献信息

• Acid–base equilibria of co-ordinated ligands. Part 1. The effect of basicity of co-ordinated nitrogen donors upon the acidity of chelating 8-aminoquinoline in some dicationic platinum(<scp>II</scp>) complexes
  作者：Giuliano Annibale、Lucio Cattalini、Francesca Guidi

  DOI：10.1039/dt9940000731

  日期：——

  Cationic complexes of the type [Pt(8NH2-quin)L2][ClO4]2, and [Pt(8NH2-quin)(L–L)][ClO4]2(8NH2-quin = 8-aminoquinoline), where L and L–L are mono- and bi-dentate nitrogen donors respectively, have been prepared. In aqueous solution, they undergo reversible deprotonation of the amino group of the quinoline ligand. The corresponding ionization constants (Kac) have been determined by UV/VIS spectrophotometry

  [Pt（8NH 2 -quin）L 2 ] [ClO 4 ] 2和[Pt（8NH 2 -quin）（L–L）] [ClO 4 ] 2（8NH 2 -quin = 8型）的阳离子络合物氨基喹啉），其中L和L–L分别是单齿和双齿氮供体。在水溶液中，它们经历喹啉配体的氨基的可逆去质子化。相应的电离常数（K a c）已通过25°C和I = 0.1 mol dm –3的UV / VIS分光光度法测定。线性自由能关系p K a c =α+βpķ一个大号被验证为对位取代的phyridines，P ķ一个大号参照L的水的碱度在25℃。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Pt: MVol.D, 129, page 290 - 292
  作者：

  DOI：——

  日期：——
• Williams, C. G., Journal fur praktische Chemie (Leipzig 1954), 1859, vol. 76, p. 251 - 252
  作者：Williams, C. G.

  DOI：——

  日期：——
• Williams, C. G., 1858, vol. 16, p. 346 - 346
  作者：Williams, C. G.

  DOI：——

  日期：——