N-[(E,2S,3R)-1-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4S,5S,6R)-4-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxyoctadec-4-en-2-yl]tetracosanamide | 118322-73-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 鞘脂
• 英文名称: N-[(E,2S,3R)-1-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4S,5S,6R)-4-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxyoctadec-4-en-2-yl]tetracosanamide
• CAS: 118322-73-9
• 化学式: C₆₂H₁₁₆N₂O₁₈
• 分子量: 1177.61
• InChiKey: UTPYCQTYGPLGHV-JMEBFVITSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.9
• 重原子数：
  82
• 可旋转键数：
  48
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  316
• 氢给体数：
  12
• 氢受体数：
  18

反应信息

• 作为产物：
  描述：

  [(2R,3R,4S,5R,6R)-5-[(2S,3R,4S,5S,6R)-4-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-3,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-4-acetyloxy-6-(acetyloxymethyl)-2-[(Z,2S,3R)-3-[tert-butyl(diphenyl)silyl]oxy-2-(tetracosanoylamino)octadec-4-enoxy]oxan-3-yl] 2,2-dimethylpropanoate 生成 N-[(E,2S,3R)-1-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4S,5S,6R)-4-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxyoctadec-4-en-2-yl]tetracosanamide
  参考文献：
  名称：

  OGAVA, TOMOYA;SATO, SUSUMU;ITO, YUKINARI

  摘要：

  DOI：

文献信息

• An efficient approach to stereoselective glycosylation of ceramide derivatives: Use of pivaloyl group as a stereocontrolling auxiliary
  作者：Susumu Sato、Shigeki Nunomura、Takahisa Nakano、Yukishige Ito、Tomoya Ogawa

  DOI：10.1016/s0040-4039(00)80426-8

  日期：1988.1