1-ethyl-4,4-dimethyl-piperidine-2,6-dione | 58366-56-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-ethyl-4,4-dimethyl-piperidine-2,6-dione
• 英文别名: 1-Aethyl-4,4-dimethyl-piperidin-2,6-dion；1-Ethyl-4,4-dimethylpiperidine-2,6-dione
• CAS: 58366-56-6
• 化学式: C₉H₁₅NO₂
• 分子量: 169.224
• InChiKey: GDLBAVNFZOUSKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3,3-二甲基戊二酸酐 、 乙胺 生成 1-ethyl-4,4-dimethyl-piperidine-2,6-dione
  参考文献：
  名称：

  Benica; Wilson, Journal of the American Pharmaceutical Association (1912), 1950, vol. 39, p. 451,453

  摘要：

  DOI：

文献信息

• HETEROCYCLIC ANTIVIRAL COMPOUNDS
  申请人：Li Jim

  公开号：US20100111900A1

  公开（公告）日：2010-05-06

  Compounds having the formula I wherein R 1 , R 2 , R 3a , R 3b , R 3c , R 4 , R 5 and p are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.

  具有以下化学式I的化合物，其中R1、R2、R3a、R3b、R3c、R4、R5和p的定义如本文所述，是丙型肝炎病毒NS5b聚合酶抑制剂。还公开了用于治疗HCV感染和抑制HCV复制的组合物和方法。
• ORGANIC COMPOUNDS AND THEIR USES
  申请人：Brandl Trixl

  公开号：US20100204159A1

  公开（公告）日：2010-08-12

  The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.

  本申请描述了对人类疾病的治疗、预防和/或改善有用的有机化合物。
• P1-NONEPIMERIZABLE KETOAMIDE INHIBITORS OF HCV NS3 PROTEASE
  申请人：Venkatraman Srikanth

  公开号：US20100074867A1

  公开（公告）日：2010-03-25

  The present invention discloses novel compounds, which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

  本发明揭示了具有HCV蛋白酶抑制活性的新化合物，以及制备这些化合物的方法。在另一种实施方式中，本发明揭示了包含这些化合物的药物组合物，以及使用它们治疗与HCV蛋白酶相关的疾病的方法。
• Highly-fluorescent and photo-stable chromophores for wavelength conversion
  申请人：NITTO DENKO CORPORATION

  公开号：US10461201B2

  公开（公告）日：2019-10-29

  The invention provides highly fluorescent materials comprising a heterocyclic systems represented by formula (I): wherein i is 0 and Het is wherein X is selected from the group consisting of —N(A0)-. The chromophores are particularly useful for absorption and emission of photons in the visible and near infrared wavelength range. The photo-stable highly luminescent chromophores are useful in various applications, including in wavelength conversion films. Wavelength conversion films have the potential to significantly enhance the solar harvesting efficiency of photovoltaic or solar cell devices.

  本发明提供了由式 (I) 所代表的杂环系统组成的高荧光材料： 其中 i 为 0，Het 为 其中 X 选自 -N(A0)-。这些发色团特别适用于吸收和发射可见光和近红外波长范围内的光子。光稳定的高发光发色团可用于各种应用，包括波长转换薄膜。波长转换薄膜有可能显著提高光伏或太阳能电池装置的太阳能收集效率。
• Kondo, Yasuhiko; Nonaka, Osamu; Iwasaki, Kazuhiko, Journal of the Chemical Society. Perkin transactions II, 1994, # 3, p. 473 - 478
  作者：Kondo, Yasuhiko、Nonaka, Osamu、Iwasaki, Kazuhiko、Kuwamoto, Tomoyuki、Takagi, Tatsuya

  DOI：——

  日期：——