bis-((N,N-diethyl)amino)ethoxyvinylphosphine | 1315511-25-1

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: bis-((N,N-diethyl)amino)ethoxyvinylphosphine
• 英文别名: P-(2-ethoxyvinyl)-N,N,N',N'-tetraethylphosphonous diamide；N-[diethylamino(2-ethoxyethenyl)phosphanyl]-N-ethylethanamine
• CAS: 1315511-25-1
• 化学式: C₁₂H₂₇N₂OP
• 分子量: 246.333
• InChiKey: MLFJIRMSGJWMHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.49
• 重原子数：
  16.0
• 可旋转键数：
  9.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  15.71
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  bis-((N,N-diethyl)amino)ethoxyvinylphosphine 在 正丁基锂 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 3.0h， 生成 N1,N1,N1,N1-tetraethyl-1λ5-phosphinine-1,1-diamine
  参考文献：
  名称：

  Electrocyclization of Phosphahexatrienes: An Approach to λ⁵-Phosphinines

  摘要：

  We experimentally verified an assumption that the substitution of a carbon atom with a pentavalent phosphorus atom in 1-alkoxy (dialkylamino) hexatrienes will not hamper its ability to electrocyclize. A series of 1-, 3-, and 5-phosphahexatrienes were synthesized. It was shown that parent lambda(5)-phosphinines could be synthesized by electrocyclization of the 3- and 5-phosphahexatrienes. The resultant electrocyclization is a convenient method for the synthesis of parent lambda(5)-phosphinines bearing different substituents on the phosphorus atom.

  DOI：

  10.1021/jo200847r
• 作为产物：
  描述：

  (2-ethoxyvinyl)phosphonous dichloride 、 二乙胺 在 三乙胺 作用下， 以 正己烷 为溶剂， 以69%的产率得到bis-((N,N-diethyl)amino)ethoxyvinylphosphine
  参考文献：
  名称：

  Electrocyclization of Phosphahexatrienes: An Approach to λ⁵-Phosphinines

  摘要：

  We experimentally verified an assumption that the substitution of a carbon atom with a pentavalent phosphorus atom in 1-alkoxy (dialkylamino) hexatrienes will not hamper its ability to electrocyclize. A series of 1-, 3-, and 5-phosphahexatrienes were synthesized. It was shown that parent lambda(5)-phosphinines could be synthesized by electrocyclization of the 3- and 5-phosphahexatrienes. The resultant electrocyclization is a convenient method for the synthesis of parent lambda(5)-phosphinines bearing different substituents on the phosphorus atom.

  DOI：

  10.1021/jo200847r

文献信息

• Versatile Approach to 3-Phosphahexatrienes Bearing Low Coordinated Phosphorus
  作者：Anna I. Arkhypchuk、Yurii V. Svyaschenko、Sascha Ott

  DOI：10.1080/10426507.2014.983596

  日期：2015.6.3

  GRAPHICAL ABSTRACT Abstract λ3-phosphahexatrienes were prepared from ethoxyvinyl phosphinophosphonates using the phospha-Wittig–Horner reaction. The title compounds can be easily prepared in three steps starting from dichlorophosphines with good overall yields. Although these were found to be thermally unstable, these can be trapped, for instance, with methanol. The resulting methoxyphosphines are

  图形摘要 摘要 λ3-磷酸六三烯是使用磷酸-Wittig-Horner 反应从乙氧基乙烯基膦酸酯制备的。标题化合物可以从二氯膦开始以良好的总产率通过三个步骤轻松制备。虽然这些被发现是热不稳定的，但它们可以被捕获，例如，用甲醇。在醛原料具有更大取代基的情况下，以高产率分离所得甲氧基膦。