1-氮杂-3,5-二甲基-4,6-二氧双环[ 3.3.0 ]辛烷 | 26562-68-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 原羧酸衍生物
• 中文名称: 1-氮杂-3,5-二甲基-4,6-二氧双环[ 3.3.0 ]辛烷
• 中文别名: 1-氮杂-3,5-二甲基-4,6-二氧杂二环[3.3.0]辛烷；1-氮杂-3,5-二甲基-4,6-二氧双环[3.3.0]辛烷
• 英文名称: 3,5-Dimethyl-4,6-dioxa-1-aza-bicyclo<3.3.0>octan
• 英文别名: Tetrahydro-2,7a-dimethyl-7aH-oxazolo(2,3-b)oxazole；6,7a-dimethyl-2,3,5,6-tetrahydro-[1,3]oxazolo[2,3-b][1,3]oxazole
• CAS: 26562-68-5
• 化学式: C₇H₁₃NO₂
• 分子量: 143.186
• InChiKey: AFRVEOQRRBJDRI-UHFFFAOYSA-N

物化性质

• 沸点：
  86 °C
• 密度：
  1.1095 (rough estimate)
• 稳定性/保质期：

  遵照规定使用和储存，则不会发生分解。

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

SDS

Name:	1-Aza-3 5-Dimethyl-4 6-Dioxabicyclo-(3.3.0)Octane 98% Material Safety Data Sheet
Synonym:	None known
CAS:	26562-68-5

Section 1 - Chemical Product MSDS Name:1-Aza-3 5-Dimethyl-4 6-Dioxabicyclo-(3.3.0)Octane 98% Material Safety Data Sheet
Synonym:None known

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
26562-68-5	1-Aza-3,5-Dimethyl-4,6-Dioxabicyclo-(3	98	247-805-5

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.)

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 26562-68-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Clear liquid
Color: clear colorless to amber
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula:
Molecular Weight:

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 26562-68-5 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1-Aza-3,5-Dimethyl-4,6-Dioxabicyclo-(3.3.0)Octane, 98% - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 26562-68-5: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 26562-68-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 26562-68-5 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  1-氮杂-3,5-二甲基-4,6-二氧双环[ 3.3.0 ]辛烷 、 苯酚 生成 N-(2-Phenoxyethyl)-N-(2-hydroxyisopropyl)-acetamid
  参考文献：
  名称：

  Bicyclic Amide Acetals. Synthesis and Reactions

  摘要：

  本文综述了双环酰胺缩醛（一类新的高活性化合物）的合成和性质。所述双环酰胺缩醛的反应为制备新型物质提供了丰富的可能性。

  DOI：

  10.1055/s-1971-21663
• 作为产物：
  描述：

  1-(2-羟基-乙基氨基)-丙烷-2-醇 、 乙腈 在 sodium 作用下， 生成 1-氮杂-3,5-二甲基-4,6-二氧双环[ 3.3.0 ]辛烷
  参考文献：
  名称：

  Burzin,K.; Feinauer,R., Angewandte Chemie, 1973, vol. 85, p. 1055 - 1056

  摘要：

  DOI：

文献信息

• Feinauer,R.; Henckel,E., Justus Liebigs Annalen der Chemie, 1968, vol. 716, p. 135 - 142
  作者：Feinauer,R.、Henckel,E.

  DOI：——

  日期：——
• Bicyclic Amide Acetals. Synthesis and Reactions
  作者：Roland FEINAUER

  DOI：10.1055/s-1971-21663

  日期：——

  The synthesis and properties of bicyclic amide acetals, a new class of very reactive compounds, are reviewed. The reactions of the bicyclic amide acetals described have a wealth of possibilities for the preparation of new classes of substances.

  本文综述了双环酰胺缩醛（一类新的高活性化合物）的合成和性质。所述双环酰胺缩醛的反应为制备新型物质提供了丰富的可能性。
• Burzin,K.; Feinauer,R., Angewandte Chemie, 1973, vol. 85, p. 1055 - 1056
  作者：Burzin,K.、Feinauer,R.

  DOI：——

  日期：——