3-(二乙氧基(甲基)甲硅烷基)-N,N-二甲基丙烷-1-胺 | 82925-57-3

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: 3-(二乙氧基(甲基)甲硅烷基)-N,N-二甲基丙烷-1-胺
• 英文名称: 3-dimethylaminopropyldiethoxymethylsilane
• 英文别名: <3-(dimethylamino)propyl>diethoxymethylsilane；3-dimethylamino-diethoxymethylsilane；3-(diethoxy(methyl)silyl)-N,N-dimethylpropan-1-amine；3-dimethylaminopropylmethyldiethoxysilane；3-Dimethylaminopropyl(diethoxy)methylsilane；3-[diethoxy(methyl)silyl]-N,N-dimethylpropan-1-amine
• CAS: 82925-57-3
• 化学式: C₁₀H₂₅NO₂Si
• 分子量: 219.399
• InChiKey: ZZNRMMYTKJBVPD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.08
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-(二乙氧基(甲基)甲硅烷基)-N,N-二甲基丙烷-1-胺 、 N-bromoacetyl-L-alanine hexadecyl ester 以 乙醇 、 二氯甲烷 为溶剂， 反应 42.0h， 以75%的产率得到
  参考文献：
  名称：

  A Condensable Amphiphile with a Cleavable Tail as a “Lizard” Template for the Sol−Gel Synthesis of Functionalized Mesoporous Silica

  摘要：

  Use of a dialkoxysilane-containing, condensable alanine amphiphile with a cleavable hexadecyl ester tail (1) as a "lizard" template for sol-gel synthesis results in the formation of a mesoporous silicate (2) whose channels are filled with an organic group of the template. Treatment of 2 with aqueous HCl allows selective cleavage of the ester moiety to leave nanochannels (3) whose surface is densely covered with alanine-CO2H. According to XRD and TEM, 2, on conversion into 3, can preserve its regular hexagonal structure. 3 displays a clear N2 adsorption/desorption isotherm with a BET surface area of 536 m2 g-1. 3 can also adsorb a basic guest such as NH3 up to 0.7 mmol g-1, which is 7 times greater than that observed for mesoporous silica obtained by calcination of 2.

  DOI：

  10.1021/ja039515r
• 作为产物：
  描述：

  甲基二乙氧基硅烷 、 二甲基烯丙基胺 在 dihydrogen hexachloroplatinate 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以27%的产率得到3-(二乙氧基(甲基)甲硅烷基)-N,N-二甲基丙烷-1-胺
  参考文献：
  名称：

  Kashutina, E. A.; Adrianov, A. K.; Zhdanov, A. A., Journal of general chemistry of the USSR, 1984, vol. 54, # 3, p. 582 - 585

  摘要：

  DOI：

文献信息

• Catalysis of a Peptidic Micellar Assembly Covalently Immobilized within Mesoporous Silica Channels: Importance of Amphiphilic Spatial Design
  作者：Wataru Otani、Kazushi Kinbara、Qingmin Zhang、Katsuhiko Ariga、Takuzo Aida

  DOI：10.1002/chem.200601099

  日期：2007.2.12

  Reference composite 2-MS, which is a noncovalently immobilized peptidic micelle, was virtually inactive (1% in 24 h). These observations indicate the importance of covalent immobilization of the peptidic rod micelle for catalysis. Mesostructured silicate 3-MS hybridized with a nonpeptidic, ammonium ion amphiphile (3) showed a certain catalytic activity, but the yield (12% in 24 h) of the acetal was much

  发现一种介孔结构的二氧化硅/有机复合物1-MS是由氨基酸两亲物1的棒状胶束构成的，该分子具有可凝缩的头基且可用作模板，可在乙醇中催化环己酮的缩醛化。 25摄氏度（12小时内达到50％），而未官能化的介孔二氧化硅则未发生反应。与之形成鲜明对比的是，固定化1的C16烷基尾部的水解去除导致催化活性完全消失，这表明疏水性内部结构域对于接纳环己酮的重要性。在不存在上述条件（24小时内为2％）或存在介孔二氧化硅（24小时内为7％）的情况下，与上述条件相同的条件下，未负载的肽两亲物2缩醛化效率低下。参考复合物2-MS，它是非共价固定的肽胶束，实际上是无活性的（在24小时内为1％）。这些观察结果表明肽棒胶束的共价固定对于催化的重要性。与非肽型铵离子两亲物（3）杂化的介孔结构的硅酸盐3-MS具有一定的催化活性，但乙缩醛的收率（24小时为12％）远低于以1-MS为催化剂的收率。表面固定有1的无定形二氧化硅的活
• Platinum Oxide (PtO₂): A Potent Hydrosilylation Catalyst
  作者：Nicolas Sabourault、Gérard Mignani、Alain Wagner、Charles Mioskowski

  DOI：10.1021/ol025658r

  日期：2002.6.1

  [GRAPHICS]Platinum oxide was found to be a versatile and powerful hydrosilylation catalyst upon a wide variety of functionalized alkenes and especially aminated alkenes. Moreover, highly reproducible results and easy removal make this new catalyst a useful tool for hydrosilylation reaction.
• A new platinum vapor-derived highly efficient hydrosilylation catalyst: NMR structural investigation
  作者：Gloria Uccello-Barretta、Federica Balzano、Claudio Evangelisti、Patrizio Raffa、Alessandro Mandoli、Samuele Nazzi、Giovanni Vitulli

  DOI：10.1016/j.jorganchem.2008.01.024

  日期：2008.4

  The structural features of a highly efficient hydrosilylation catalyst generated by reaction of Pt vapor and a mixture of mesitylene and 1,3-divinyltetramethyldisiloxane (DVS) were investigated by mono- and bidimensional NMR analyses. The structure around the Pt atoms was highlighted and compared with a commercial sample (Karstedt catalyst) and previously reported Pt vapor-derived system. (C) 2008 Elsevier B.V. All rights reserved.
• Saratov, I. E.; Shpak, I. V.; Markov, S. A., Journal of general chemistry of the USSR, 1981, vol. 51, p. 1746 - 1749
  作者：Saratov, I. E.、Shpak, I. V.、Markov, S. A.、Lazarev, S. Ya.、Reikhsfel'd, V. O.

  DOI：——

  日期：——
• KASHUTINA, EH. A.;ANDRIANOV, A. K.;ZHDANOV, A. A.;OLENIN, A. V.;ZUBOV, V.+, ZH. OBSHCH. XIMII, 1984, 54, N 3, 657-662
  作者：KASHUTINA, EH. A.、ANDRIANOV, A. K.、ZHDANOV, A. A.、OLENIN, A. V.、ZUBOV, V.+

  DOI：——

  日期：——